Detailed information NTG0811059

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P7F77_RS10090
• Genome accession: NZ_CP121204
• Coordinates: 2039008..2040051 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017129.1
• Uniprot ID: A0A0U1MRG1
• Organism: Staphylococcus aureus strain SA0907
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2034008..2045051

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P7F77_RS10060 (P7F77_10065)	-	2034429..2035685 (-)	1257	WP_001793428.1	aminopeptidase	-
P7F77_RS10065 (P7F77_10070)	-	2035688..2035888 (-)	201	WP_001813025.1	DUF1128 family protein	-
P7F77_RS10070 (P7F77_10075)	-	2036035..2036499 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P7F77_RS10075 (P7F77_10080)	-	2036506..2036781 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P7F77_RS10080 (P7F77_10085)	-	2037059..2038276 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
P7F77_RS10085 (P7F77_10090)	vraR	2038389..2039018 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P7F77_RS10090 (P7F77_10095)	vraS	2039008..2040051 (-)	1044	WP_001017129.1	sensor histidine kinase	Regulator
P7F77_RS10095 (P7F77_10100)	liaF	2040048..2040749 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P7F77_RS10100 (P7F77_10105)	-	2040764..2041150 (-)	387	WP_001110183.1	hypothetical protein	-
P7F77_RS10105 (P7F77_10110)	map	2041367..2042125 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
P7F77_RS10110 (P7F77_10115)	-	2042712..2043698 (+)	987	WP_000999711.1	aromatic acid exporter family protein	-
P7F77_RS10115 (P7F77_10120)	-	2043874..2044290 (-)	417	WP_025174454.1	hypothetical protein	-
P7F77_RS10120 (P7F77_10125)	-	2044319..2044428 (-)	110	Protein_1955	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40060.56 Da
• Isoelectric Point: 6.0577

>NTDB_id=811059 P7F77_RS10090 WP_001017129.1 2039008..2040051(-) (vraS) [Staphylococcus aureus strain SA0907]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQILILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=811059 P7F77_RS10090 WP_001017129.1 2039008..2040051(-) (vraS) [Staphylococcus aureus strain SA0907]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCT
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCGAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0U1MRG1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997