Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   P7F70_RS07610 Genome accession   NZ_CP121201
Coordinates   1517022..1519280 (+) Length   752 a.a.
NCBI ID   WP_278025329.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SP28     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1519337..1520628 1517022..1519280 flank 57


Gene organization within MGE regions


Location: 1517022..1520628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7F70_RS07610 (P7F70_07615) clpE 1517022..1519280 (+) 2259 WP_278025329.1 ATP-dependent Clp protease ATP-binding subunit Regulator

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83641.77 Da        Isoelectric Point: 4.8345

>NTDB_id=811008 P7F70_RS07610 WP_278025329.1 1517022..1519280(+) (clpE) [Streptococcus pluranimalium strain SP28]
MLCQNCQLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPKNNLLSNLGRENASSSMNPFFDDFFGDLNNFRAFSGDLPN
SPKTQSGGQGGNNGIGNRHPNAPLGGAQQKPQGLLEEFGINITDIARQGDIDPVIGRDEEILRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDADVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEIVGAG
NAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSP
DAIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPQEIDQRLVEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKIDDHDTPVITEKNIEAIIEQKTNIPVGDLKEKEQSQLIHLADDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLNQLGDFFSPEFMN
RFDGIIEFKALEKENLLTIVDLMLKDVNDRLATNGLHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLE
NPSEKNLRAIMTSNGNIIIKSNTKAEALVEEN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=811008 P7F70_RS07610 WP_278025329.1 1517022..1519280(+) (clpE) [Streptococcus pluranimalium strain SP28]
ATGCTTTGTCAAAATTGTCAATTAAACGAATCAACTATCCATTTATATACTAATGTTAATGGTAAACAGAAACAAGTCGA
TCTTTGCCAAAACTGTTATCAAATTATGAAAACAGATCCCAAAAACAACCTTTTATCTAATCTGGGTCGAGAAAACGCAT
CATCTTCTATGAATCCATTTTTTGATGATTTCTTCGGTGACTTAAATAACTTCCGTGCCTTCAGCGGTGACCTTCCAAAC
AGTCCTAAAACACAATCTGGTGGTCAGGGAGGAAACAATGGAATTGGAAATCGTCATCCAAATGCTCCACTAGGCGGTGC
TCAACAAAAGCCTCAAGGACTCTTAGAAGAGTTCGGTATTAATATCACTGATATTGCACGCCAAGGCGATATTGATCCCG
TTATTGGTCGCGATGAAGAAATCCTTCGTGTTATCGAAATTCTAAACCGTCGTACCAAAAATAATCCTGTCCTCATTGGT
GAGCCAGGTGTTGGTAAAACTGCTGTCGTTGAAGGACTGGCTCAAAAGATTGTTGACGCTGATGTTCCTCAAAAACTCCA
AGGAAAGCAAGTCATCCGTTTGGATGTTGTCAGCCTTGTTCAGGGGACAGGCATCCGTGGACAATTTGAAGAACGTATGC
AAAAACTCATGGAAGAAATCCGTAATCGTCAAGATGTGATTCTCTTCATTGATGAGATTCATGAGATTGTTGGTGCAGGT
AATGCTGGTGATGGAAACATGGACGCCGGCAATATCCTAAAACCTGCTCTAGCTCGTGGTGAGCTACAACTAGTCGGTGC
TACTACTCTCAATGAATATCGTATCATTGAAAAAGATGCTGCTCTGGAACGTCGTATGCAGCCCGTCAAAGTTGATGAGC
CAAGTGTTGAGGAAACTATCACCATCTTAAAAGGTATTCAACCAAAATACGAAGACTATCACCATGTCAAATATAGCCCT
GATGCGATTGAAGCGGCAGCTATCCTTTCAAATCGTTACATTCAAGATCGCTTCCTTCCAGATAAGGCTATCGATCTACT
TGATGAAGCTGGATCTAAAATGAATTTAACCTTAAATTTTGTTGATCCACAAGAAATCGATCAACGTCTGGTGGAAGCCG
AAAACCTCAAAGCTCAAGCGACTCGAGATGAAGATTATGAACGCGCAGCTTATTTCCGTGACCAAATTGCTAAATACAAA
GAAATGCAAGCGCAAAAAATCGATGACCACGATACTCCAGTCATCACTGAAAAAAATATCGAAGCCATCATTGAACAAAA
AACTAATATTCCAGTCGGCGATCTCAAAGAAAAAGAACAAAGTCAATTAATTCATTTGGCTGACGACCTTAAATCACACG
TTATTGGACAAGACGATGCTGTTGATAAAATTGCAAAAGCCATTCGTCGTAACCGTGTCGGACTTGGTTCGCCAAATCGC
CCAATCGGTTCCTTCCTCTTTGTTGGTCCAACTGGTGTCGGTAAAACTGAACTCTCAAAACAACTAGCAATCGAGCTCTT
TGGTTCAGCAGACAGCATGATTCGCTTTGATATGTCCGAGTACATGGAAAAACATGCCGTCGCCAAACTTGTCGGAGCTC
CTCCAGGTTATGTTGGTTATGAAGAAGCTGGTCAATTAACAGAAAAAGTTCGTCGCAATCCATACTCACTCATTCTCTTG
GATGAAGTTGAGAAAGCTCACCCAGATGTTATGCATATGTTCTTACAAGTTCTTGACGATGGTCGTTTGACTGATGGTCA
AGGCCGTACCGTTAGCTTCAAAGATACCATTATCATCATGACCTCGAATGCTGGAACAGGCAAGGTTGAAGCTTCTGTTG
GATTTGGAGCAGCTCGTGAAGGTCGTACCAACTCCGTTCTTAACCAACTTGGAGACTTCTTTAGCCCAGAATTCATGAAC
CGTTTTGACGGTATTATCGAATTCAAAGCCCTTGAAAAAGAAAATCTCCTTACTATTGTTGATCTCATGCTCAAAGATGT
CAATGATAGACTTGCTACCAACGGTCTTCACCTTGATGTCACCGAGAAAGTTAAGGAAAAATTGGTTGATCTTGGCTATG
ATCCAAAAATGGGAGCTCGTCCACTTCGCAGAACAATTCAAGACCATATCGAAGATGCTATCACAGATTTCTATCTTGAA
AATCCTTCAGAGAAAAATCTCCGTGCCATCATGACTTCTAATGGAAACATCATTATCAAATCAAATACGAAAGCTGAAGC
TCTCGTAGAAGAAAACTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(295-392)

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-726)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

86.418

99.867

0.863
  clpE Streptococcus pneumoniae Rx1

82.781

100

0.831
  clpE Streptococcus pneumoniae D39

82.781

100

0.831
  clpE Streptococcus pneumoniae R6

82.781

100

0.831
  clpE Streptococcus pneumoniae TIGR4

82.781

100

0.831
  clpC Lactococcus lactis subsp. cremoris KW2

75.733

99.734

0.755
  clpC Bacillus subtilis subsp. subtilis str. 168

49.354

92.686

0.457
  clpC Streptococcus pneumoniae Rx1

47.368

83.378

0.395
  clpC Streptococcus pneumoniae D39

47.368

83.378

0.395
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.468

84.707

0.394
  clpC Streptococcus pneumoniae TIGR4

47.209

83.378

0.394
  clpC Streptococcus mutans UA159

47.182

82.58

0.39
  clpC Streptococcus thermophilus LMD-9

46.057

84.309

0.388
  clpC Streptococcus thermophilus LMG 18311

45.728

84.043

0.384