Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   P8R99_RS09165 Genome accession   NZ_CP121160
Coordinates   1741261..1741590 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae strain S5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1736261..1746590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS09150 - 1738819..1739184 (+) 366 WP_000285373.1 DUF1033 family protein -
  P8R99_RS09155 comYA 1739356..1740327 (+) 972 WP_000250799.1 competence type IV pilus ATPase ComGA Machinery gene
  P8R99_RS09160 comYB 1740221..1741264 (+) 1044 WP_228322108.1 competence type IV pilus assembly protein ComGB Machinery gene
  P8R99_RS09165 comGC/cglC 1741261..1741590 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  P8R99_RS09170 comYD 1741565..1741978 (+) 414 WP_017646959.1 competence type IV pilus minor pilin ComGD Machinery gene
  P8R99_RS09175 comGE 1741950..1742249 (+) 300 WP_025195478.1 competence type IV pilus minor pilin ComGE -
  P8R99_RS09180 comGF 1742203..1742664 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  P8R99_RS09185 comGG 1742642..1743013 (+) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG -
  P8R99_RS09190 comYH 1743128..1744102 (+) 975 WP_001008568.1 class I SAM-dependent methyltransferase Machinery gene
  P8R99_RS09195 - 1744134..1745327 (+) 1194 WP_000047537.1 acetate kinase -
  P8R99_RS09200 - 1745479..1745685 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  P8R99_RS09205 - 1745744..1745881 (+) 138 WP_079263416.1 hypothetical protein -
  P8R99_RS09210 - 1745984..1746376 (+) 393 WP_001265365.1 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=810689 P8R99_RS09165 WP_000793380.1 1741261..1741590(+) (comGC/cglC) [Streptococcus agalactiae strain S5]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=810689 P8R99_RS09165 WP_000793380.1 1741261..1741590(+) (comGC/cglC) [Streptococcus agalactiae strain S5]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495