Detailed information NTG0810668

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: P8R99_RS04605
• Genome accession: NZ_CP121160
• Coordinates: 912632..913921 (-)
• Length: 429 a.a.
• NCBI ID: WP_000432963.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain S5
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 907632..918921

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8R99_RS04595	raiA	911336..911890 (-)	555	WP_000599096.1	ribosome-associated translation inhibitor RaiA	-
P8R99_RS04600	-	911967..912632 (-)	666	WP_017647122.1	ComF family protein	-
P8R99_RS04605	comFA/cflA	912632..913921 (-)	1290	WP_000432963.1	DEAD/DEAH box helicase	Machinery gene
P8R99_RS04610	-	913977..914621 (+)	645	WP_001108150.1	YigZ family protein	-
P8R99_RS04615	cysK	914712..915638 (+)	927	WP_000036946.1	cysteine synthase A	-
P8R99_RS04620	-	915790..916878 (-)	1089	WP_278043362.1	glycerol dehydrogenase	-
P8R99_RS04625	-	916946..917614 (-)	669	WP_000394892.1	fructose-6-phosphate aldolase	-

Sequence

Protein

• Length: 429 a.a.
• Molecular weight: 48689.51 Da
• Isoelectric Point: 9.9941

>NTDB_id=810668 P8R99_RS04605 WP_000432963.1 912632..913921(-) (comFA/cflA) [Streptococcus agalactiae strain S5]
MENYLGRLWTKAQLSEQLRKIAISLPSFIKKGSDYICTRCSSSVAKNCQLPTGNYYCRECIVFGRVTSNENLYYFPQKTF
SKTNSLKWKGGLTPYQNEVSEELLKGISSKENLLVHAVTGAGKTEMIYHSVAKVIDTGGSVCIASPRIDVCLELHKRLSN
DFRCAITLMHGESPSYQRSPLTIATTHQLLKFYHAFDLLIVDEVDAFPYVDNPILYHGVKQALKENGTSIFLTATSTTEL
ERKVARKELKKLHLARRFHANPLVIPEMVWVSGIQKSLQTQKLPPKLYQLINKQRQTRYPLLLFFPHISEGQVFTEMLRQ
AFPMEKIGFVSSKSTSRLKLVQDFRDNKLSILVSTTILERGVTFPSVDVFVIQANHHLFTKSSLVQISGRVGRALERPEG
LLYFLHDGKSKSMHQAIKEIKNMNHIGGF

Nucleotide

• Length: 1290 bp

>NTDB_id=810668 P8R99_RS04605 WP_000432963.1 912632..913921(-) (comFA/cflA) [Streptococcus agalactiae strain S5]
ATGGAAAATTATTTAGGTAGACTTTGGACAAAAGCACAATTATCTGAGCAACTTAGAAAAATTGCAATTAGCTTGCCATC
TTTTATAAAGAAAGGAAGCGACTATATTTGTACCCGATGCTCTAGTTCTGTTGCCAAAAATTGCCAATTACCAACTGGAA
ATTATTATTGTAGAGAATGTATAGTTTTTGGAAGAGTTACTAGTAATGAAAATTTATATTATTTCCCACAAAAAACATTT
TCTAAAACGAATTCTTTAAAATGGAAAGGGGGACTGACACCTTATCAAAATGAGGTTTCAGAAGAGTTGTTGAAAGGTAT
TTCAAGTAAGGAAAATCTTCTTGTTCATGCTGTGACAGGGGCTGGTAAAACAGAAATGATATACCACTCTGTCGCCAAAG
TAATTGATACTGGAGGAAGCGTTTGTATTGCCAGTCCTAGAATTGATGTTTGTTTAGAATTGCATAAGCGACTTTCAAAC
GATTTTAGATGTGCCATAACATTAATGCATGGAGAATCTCCTTCTTATCAGAGATCCCCTTTAACTATTGCCACAACACA
TCAATTGTTAAAATTTTATCATGCTTTTGATTTGCTAATTGTTGATGAAGTTGATGCTTTTCCATATGTCGACAACCCGA
TACTATACCATGGTGTAAAACAGGCTTTAAAGGAAAACGGAACAAGTATTTTTCTGACTGCAACTTCAACGACTGAGTTA
GAAAGAAAAGTTGCAAGAAAAGAACTAAAAAAATTACATCTAGCTAGGAGATTTCATGCCAATCCGTTAGTGATACCCGA
GATGGTTTGGGTAAGTGGTATCCAGAAAAGCTTGCAGACACAAAAACTACCTCCCAAATTATATCAGCTGATAAATAAAC
AGCGACAAACGAGATATCCTTTGTTATTATTTTTCCCCCATATTTCAGAAGGTCAGGTATTCACCGAAATGTTAAGACAA
GCCTTTCCTATGGAAAAAATTGGTTTTGTTTCAAGTAAGAGCACATCTAGGTTAAAGTTAGTGCAAGATTTTCGAGATAA
CAAATTGTCTATCCTAGTGTCAACTACCATTCTAGAGAGAGGAGTAACTTTCCCTAGCGTCGACGTTTTTGTTATACAAG
CAAATCATCATTTGTTTACGAAAAGTTCCTTGGTACAAATTTCGGGAAGAGTTGGAAGAGCATTAGAAAGGCCCGAAGGG
CTCCTTTACTTCCTTCATGATGGGAAAAGTAAATCGATGCACCAAGCTATAAAGGAGATTAAAAACATGAATCATATAGG
AGGATTTTAA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (286-394)

• DEAD/DEAH box helicase (DEAD) (93-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis NCTC 12261	60.656	99.534	0.604
comFA/cflA	Streptococcus pneumoniae Rx1	60.187	99.534	0.599
comFA/cflA	Streptococcus pneumoniae D39	60.187	99.534	0.599
comFA/cflA	Streptococcus pneumoniae R6	60.187	99.534	0.599
comFA/cflA	Streptococcus mitis SK321	60.187	99.534	0.599
comFA/cflA	Streptococcus pneumoniae TIGR4	60.187	99.534	0.599
comFA	Lactococcus lactis subsp. cremoris KW2	50	91.841	0.459
comFA	Bacillus subtilis subsp. subtilis str. 168	39.066	94.872	0.371
comFA	Latilactobacillus sakei subsp. sakei 23K	36.322	100	0.368