Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   QN329_RS02910 Genome accession   NZ_CP135103
Coordinates   502129..504102 (+) Length   657 a.a.
NCBI ID   WP_000034615.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain HU36/21     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 497129..509102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN329_RS02895 (QN329_02895) argR 498573..499010 (+) 438 WP_001033152.1 arginine repressor -
  QN329_RS02900 (QN329_02900) hexA 499067..501643 (+) 2577 WP_001118381.1 DNA mismatch repair protein MutS Machinery gene
  QN329_RS02905 (QN329_02905) - 501700..501903 (-) 204 WP_000191849.1 cold-shock protein -
  QN329_RS02910 (QN329_02910) hexB 502129..504102 (+) 1974 WP_000034615.1 DNA mismatch repair endonuclease MutL Machinery gene
  QN329_RS02915 (QN329_02915) - 504134..505366 (+) 1233 WP_000657478.1 MDR family MFS transporter -
  QN329_RS02920 (QN329_02920) ruvA 505368..505958 (+) 591 WP_000272490.1 Holliday junction branch migration protein RuvA Machinery gene
  QN329_RS02925 (QN329_02925) - 505981..506532 (+) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  QN329_RS02930 (QN329_02930) cinA 506621..507880 (+) 1260 WP_001200975.1 competence/damage-inducible protein A Machinery gene
  QN329_RS02935 (QN329_02935) recA 507954..509093 (+) 1140 WP_001085741.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 657 a.a.        Molecular weight: 73808.90 Da        Isoelectric Point: 5.3704

>NTDB_id=809922 QN329_RS02910 WP_000034615.1 502129..504102(+) (hexB) [Streptococcus agalactiae strain HU36/21]
MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKY
MKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLP
ELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQSGLYYDRTKNDFFIDADTVSEPIANFTNLDKSDGSVDNDVK
NSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIID
QHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVE
SGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKM
FKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1974 bp        

>NTDB_id=809922 QN329_RS02910 WP_000034615.1 502129..504102(+) (hexB) [Streptococcus agalactiae strain HU36/21]
TTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAGTAGCGT
CGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTCTTAAAA
AGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACATCCAAA
ATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTCGATTAG
TTTAATGACAATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTGAAAAAC
AGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAATACGCCTGCCAGATTGAAATAC
ATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGTTGCTTT
TACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTATTTATG
GTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGTTTGCCT
GAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTAAACCGCTC
AATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATCCTTATC
TAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATAAGCTCA
GCAATTTCTGAGAGTCTGAAACAATATGATTTGATTCCGGATGCTTTAGAGAATTTAGCGAAAACTAGTACCCGAAGTGT
AGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGTCTGGTTTGTATTACGATAGGACTAAAAATGACTTTTTTATAG
ATGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGATGTAAAA
AACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAACTTCAT
TCATTCTCAGGACTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTTCGACTT
TTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATTATTGAT
CAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCAACAATT
GTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAGATGTTG
GTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAGGTAGAG
TCTGGCGTTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTTAGCTAT
TATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATCAGTTAG
CGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAGAAAATG
TTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(458-601)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.044

100

0.693