Detailed information NTG0809458

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLUC7005_RS11210
• Genome accession: NZ_CP120933
• Coordinates: 2229391..2230419 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis subsp. lactis strain UC7005
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2224391..2235419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC7005_RS11185 (LLUC7005_11155)	-	2224677..2225174 (-)	498	WP_003132662.1	nitroreductase family protein	-
LLUC7005_RS11190 (LLUC7005_11160)	-	2225161..2225370 (-)	210	WP_003132661.1	hypothetical protein	-
LLUC7005_RS11195 (LLUC7005_11165)	-	2225367..2226194 (-)	828	WP_014570829.1	radical SAM protein	-
LLUC7005_RS11200 (LLUC7005_11170)	-	2226187..2228310 (-)	2124	WP_003132659.1	radical SAM protein	-
LLUC7005_RS11205 (LLUC7005_11175)	-	2228413..2229270 (-)	858	WP_003132658.1	Rgg/GadR/MutR family transcriptional regulator	-
LLUC7005_RS11210 (LLUC7005_11180)	sepM	2229391..2230419 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
LLUC7005_RS11215 (LLUC7005_11185)	coaD	2230406..2230903 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LLUC7005_RS11220 (LLUC7005_11190)	rsmD	2230951..2231490 (-)	540	WP_003132655.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLUC7005_RS11225 (LLUC7005_11195)	-	2231661..2232881 (-)	1221	WP_003132654.1	MFS transporter	-
LLUC7005_RS11230 (LLUC7005_11200)	lmrP	2232965..2234189 (-)	1225	Protein_2181	multidrug efflux MFS transporter LmrP	-
LLUC7005_RS11235 (LLUC7005_11205)	-	2234377..2234871 (+)	495	WP_012898649.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=809458 LLUC7005_RS11210 WP_003132657.1 2229391..2230419(-) (sepM) [Lactococcus lactis subsp. lactis strain UC7005]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=809458 LLUC7005_RS11210 WP_003132657.1 2229391..2230419(-) (sepM) [Lactococcus lactis subsp. lactis strain UC7005]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGAAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTGGTGCCTGACTCAGGCACCAAAAAAGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491