Detailed information NTG0809431

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: LLUC7005_RS07665
• Genome accession: NZ_CP120933
• Coordinates: 1568168..1569643 (-)
• Length: 491 a.a.
• NCBI ID: WP_010906048.1
• Uniprot ID: A0A2A9ICZ0
• Organism: Lactococcus lactis subsp. lactis strain UC7005
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1563168..1574643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC7005_RS07650 (LLUC7005_07630)	murD	1564429..1565781 (-)	1353	WP_003130748.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-
LLUC7005_RS07655 (LLUC7005_07635)	-	1566272..1566613 (-)	342	WP_010906046.1	P-II family nitrogen regulator	-
LLUC7005_RS07660 (LLUC7005_07640)	-	1566745..1567986 (-)	1242	WP_014570660.1	ammonium transporter	-
LLUC7005_RS07665 (LLUC7005_07645)	covS	1568168..1569643 (-)	1476	WP_010906048.1	HAMP domain-containing histidine kinase	Regulator
LLUC7005_RS07670 (LLUC7005_07650)	covR	1569651..1570343 (-)	693	WP_003130756.1	response regulator transcription factor	Regulator
LLUC7005_RS07675 (LLUC7005_07655)	-	1570499..1571029 (-)	531	WP_003130758.1	DUF177 domain-containing protein	-
LLUC7005_RS07680 (LLUC7005_07660)	-	1571160..1571405 (-)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
LLUC7005_RS07685 (LLUC7005_07665)	-	1571561..1572025 (-)	465	WP_003130761.1	hypothetical protein	-
LLUC7005_RS07690 (LLUC7005_07670)	-	1572107..1572469 (-)	363	WP_010906050.1	TIGR02328 family protein	-
LLUC7005_RS07695 (LLUC7005_07675)	-	1572954..1573451 (-)	498	WP_226898137.1	CHAP domain-containing protein	-
LLUC7005_RS07700 (LLUC7005_07680)	-	1573545..1574381 (-)	837	WP_014570661.1	metallophosphoesterase	-

Sequence

Protein

• Length: 491 a.a.
• Molecular weight: 56195.08 Da
• Isoelectric Point: 4.8253

>NTDB_id=809431 LLUC7005_RS07665 WP_010906048.1 1568168..1569643(-) (covS) [Lactococcus lactis subsp. lactis strain UC7005]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide

• Length: 1476 bp

>NTDB_id=809431 LLUC7005_RS07665 WP_010906048.1 1568168..1569643(-) (covS) [Lactococcus lactis subsp. lactis strain UC7005]
ATGAAAAAACTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGGTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

• ArlS sensor domain (ArlS_N) (54-185)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (380-489)

• HAMP domain (HAMP) (208-258)

• His Kinase A (phospho-acceptor) domain (HisKA) (267-332)

3D structure

• AlphaFold DB: A0A2A9ICZ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	100	100	1