Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LLHP_RS12030 Genome accession   NZ_CP120921
Coordinates   2310660..2311691 (-) Length   343 a.a.
NCBI ID   WP_011677213.1    Uniprot ID   A0A166ZHD8
Organism   Lactococcus cremoris subsp. cremoris HP     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2305660..2316691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLHP_RS12005 (LLHP_12045) - 2306865..2307362 (-) 498 WP_032951474.1 nitroreductase family protein -
  LLHP_RS12010 (LLHP_12050) - 2307349..2307558 (-) 210 WP_011677212.1 hypothetical protein -
  LLHP_RS12015 (LLHP_12055) - 2307845..2308735 (+) 891 WP_081196119.1 IS982-like element IS982B family transposase -
  LLHP_RS12020 (LLHP_12060) kwcM 2308842..2310161 (-) 1320 WP_014573366.1 KxxxW cyclic peptide radical SAM maturase -
  LLHP_RS12025 (LLHP_12065) - 2310229..2310342 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  LLHP_RS12030 (LLHP_12070) sepM 2310660..2311691 (-) 1032 WP_011677213.1 SepM family pheromone-processing serine protease Regulator
  LLHP_RS12035 (LLHP_12075) coaD 2311675..2312175 (-) 501 WP_011677214.1 pantetheine-phosphate adenylyltransferase -
  LLHP_RS12040 (LLHP_12080) rsmD 2312223..2312762 (-) 540 WP_031286167.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LLHP_RS12045 (LLHP_12085) - 2312933..2314153 (-) 1221 WP_011677216.1 MFS transporter -
  LLHP_RS12050 (LLHP_12090) lmrP 2314237..2315466 (-) 1230 Protein_2345 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37398.03 Da        Isoelectric Point: 9.8499

>NTDB_id=809362 LLHP_RS12030 WP_011677213.1 2310660..2311691(-) (sepM) [Lactococcus cremoris subsp. cremoris HP]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=809362 LLHP_RS12030 WP_011677213.1 2310660..2311691(-) (sepM) [Lactococcus cremoris subsp. cremoris HP]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTATTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-339)

PDZ domain (PDZ_2)

(135-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A166ZHD8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.49