Detailed information NTG0809266

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RMP66_RS10365
• Genome accession: NZ_CP135094
• Coordinates: 2097062..2099602 (-)
• Length: 846 a.a.
• NCBI ID: WP_043032946.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1547095
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2092062..2104602

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMP66_RS10340 (RMP66_10340)	-	2093220..2093963 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
RMP66_RS10345 (RMP66_10345)	-	2093963..2094766 (-)	804	WP_014637221.1	amino acid ABC transporter permease	-
RMP66_RS10350 (RMP66_10350)	-	2094952..2095803 (-)	852	WP_013730662.1	amino acid ABC transporter substrate-binding protein	-
RMP66_RS10355 (RMP66_10355)	-	2095836..2096522 (-)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
RMP66_RS10360 (RMP66_10360)	-	2096636..2096809 (-)	174	WP_009910995.1	hypothetical protein	-
RMP66_RS10365 (RMP66_10365)	hexA	2097062..2099602 (-)	2541	WP_043032946.1	DNA mismatch repair protein MutS	Machinery gene
RMP66_RS10370 (RMP66_10370)	argR	2099617..2100057 (-)	441	WP_002937036.1	arginine repressor	-
RMP66_RS10375 (RMP66_10375)	argS	2100164..2101852 (+)	1689	WP_009910998.1	arginine--tRNA ligase	-
RMP66_RS10380 (RMP66_10380)	-	2102032..2102946 (+)	915	WP_009911000.1	SH3 domain-containing protein	-
RMP66_RS10385 (RMP66_10385)	-	2103000..2103524 (-)	525	WP_024394551.1	membrane protein	-
RMP66_RS10390 (RMP66_10390)	-	2103636..2103818 (+)	183	WP_015647552.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95084.65 Da
• Isoelectric Point: 4.8195

>NTDB_id=809266 RMP66_RS10365 WP_043032946.1 2097062..2099602(-) (hexA) [Streptococcus suis strain 1547095]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVALDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNVPAIKNILLQMDQPALTSLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELTKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTTPAPIVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=809266 RMP66_RS10365 WP_043032946.1 2097062..2099602(-) (hexA) [Streptococcus suis strain 1547095]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCATGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGCTTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATTGGCTATGCTCTGTCAGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTTCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCGACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTTGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCTAGCCGGGTATCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCTCAGACCCTTGGAAATGTCCCTGCTATCAAGAATATCTTGCTACAAATGGACC
AGCCTGCTCTGACTAGCTTGGTGGCAGGTCTGGATCCAATCCCAGAACTACACGCCCTGATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTTAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATTTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGTTATGGAACGGAAGAGTTGACTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACTCGTATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCACTCATCCTCTTTGATGAGTTGGGGCGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACTCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGACAGGATTTTGCAGACGCTTGAAAACCAAGCTCCTACTGCACCAACTACCCCAGCTCCGATAGTCGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGCAAAACTGGATAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.232	100	0.742
mutS	Pseudomonas stutzeri strain ATCC 17587	37.631	100	0.383