Detailed information NTG0809169

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RMP64_RS10445
• Genome accession: NZ_CP135093
• Coordinates: 2139436..2141976 (-)
• Length: 846 a.a.
• NCBI ID: WP_043032946.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1652329
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2134436..2146976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMP64_RS10420 (RMP64_10420)	-	2135594..2136337 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
RMP64_RS10425 (RMP64_10425)	-	2136337..2137140 (-)	804	WP_014637221.1	amino acid ABC transporter permease	-
RMP64_RS10430 (RMP64_10430)	-	2137326..2138177 (-)	852	WP_013730662.1	amino acid ABC transporter substrate-binding protein	-
RMP64_RS10435 (RMP64_10435)	-	2138210..2138896 (-)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
RMP64_RS10440 (RMP64_10440)	-	2139010..2139183 (-)	174	WP_009910995.1	hypothetical protein	-
RMP64_RS10445 (RMP64_10445)	hexA	2139436..2141976 (-)	2541	WP_043032946.1	DNA mismatch repair protein MutS	Machinery gene
RMP64_RS10450 (RMP64_10450)	argR	2141991..2142431 (-)	441	WP_002937036.1	arginine repressor	-
RMP64_RS10455 (RMP64_10455)	argS	2142538..2144226 (+)	1689	WP_009910998.1	arginine--tRNA ligase	-
RMP64_RS10460 (RMP64_10460)	-	2144406..2145320 (+)	915	WP_009911000.1	SH3 domain-containing protein	-
RMP64_RS10465 (RMP64_10465)	-	2145374..2145898 (-)	525	WP_024394551.1	membrane protein	-
RMP64_RS10470 (RMP64_10470)	-	2146010..2146192 (+)	183	WP_015647552.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95084.65 Da
• Isoelectric Point: 4.8195

>NTDB_id=809169 RMP64_RS10445 WP_043032946.1 2139436..2141976(-) (hexA) [Streptococcus suis strain 1652329]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVALDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNVPAIKNILLQMDQPALTSLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELTKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTTPAPIVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=809169 RMP64_RS10445 WP_043032946.1 2139436..2141976(-) (hexA) [Streptococcus suis strain 1652329]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCATGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGCTTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATTGGCTATGCTCTGTCAGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTTCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCGACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTTGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCTAGCCGGGTATCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCTCAGACCCTTGGAAATGTCCCTGCTATCAAGAATATCTTGCTACAAATGGACC
AGCCTGCTCTGACTAGCTTGGTGGCAGGTCTGGATCCAATCCCAGAACTACACGCCCTGATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTTAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATTTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGTTATGGAACGGAAGAGTTGACTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACTCGTATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCACTCATCCTCTTTGATGAGTTGGGGCGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACTCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGACAGGATTTTGCAGACGCTTGAAAACCAAGCTCCTACTGCACCAACTACCCCAGCTCCGATAGTCGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGCAAAACTGGATAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.232	100	0.742
mutS	Pseudomonas stutzeri strain ATCC 17587	37.631	100	0.383