Detailed information NTG0809072

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RMQ61_RS11260
• Genome accession: NZ_CP135090
• Coordinates: 2303651..2306191 (-)
• Length: 846 a.a.
• NCBI ID: WP_313920841.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ID48908
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2298651..2311191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMQ61_RS11235 (RMQ61_11240)	-	2299809..2300552 (-)	744	WP_014638810.1	amino acid ABC transporter ATP-binding protein	-
RMQ61_RS11240 (RMQ61_11245)	-	2300552..2301355 (-)	804	WP_024382666.1	amino acid ABC transporter permease	-
RMQ61_RS11245 (RMQ61_11250)	-	2301541..2302392 (-)	852	WP_313920840.1	amino acid ABC transporter substrate-binding protein	-
RMQ61_RS11250 (RMQ61_11255)	-	2302425..2303111 (-)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
RMQ61_RS11255 (RMQ61_11260)	-	2303225..2303398 (-)	174	WP_002941962.1	hypothetical protein	-
RMQ61_RS11260 (RMQ61_11265)	hexA	2303651..2306191 (-)	2541	WP_313920841.1	DNA mismatch repair protein MutS	Machinery gene
RMQ61_RS11265 (RMQ61_11270)	argR	2306206..2306646 (-)	441	WP_002937036.1	arginine repressor	-
RMQ61_RS11270 (RMQ61_11275)	argS	2306753..2308441 (+)	1689	WP_002937037.1	arginine--tRNA ligase	-
RMQ61_RS11275 (RMQ61_11280)	-	2308621..2309535 (+)	915	WP_313920842.1	SH3 domain-containing protein	-
RMQ61_RS11280 (RMQ61_11285)	-	2309588..2310109 (-)	522	WP_024385544.1	hypothetical protein	-
RMQ61_RS11285 (RMQ61_11290)	-	2310221..2310403 (+)	183	WP_002937045.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95063.49 Da
• Isoelectric Point: 4.7983

>NTDB_id=809072 RMQ61_RS11260 WP_313920841.1 2303651..2306191(-) (hexA) [Streptococcus suis strain ID48908]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTNTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLERADRILQTLENQAPTAPANPAPSVV
EEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=809072 RMQ61_RS11260 WP_313920841.1 2303651..2306191(-) (hexA) [Streptococcus suis strain ID48908]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCAGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTTGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAAGATGAGGTGACAGAGGATGTCCAATTGATTGATAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTTCACTATGAAATCAAGGACTATCTACAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCACGGTAGTTTGTACTGGTTGTTAGACGAAACCAAGACAGCTATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAAGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCTAGCCGGGTATCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAGGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
GCGTGAGGGAGCGGGCTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCATCTGGTATCAACAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATTTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGTTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTATGAGATTTTCATGCGGATTCGCCAAGAGGTTGAAAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GGACTATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCAATACGCATATGCAACTAATTACAGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCAGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTACCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGTTCGCTCATCCTCTTTGACGAACTTGGACGTGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCCAAGACTCTTTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAGTTAT
TGGAGCGGGCGGATAGGATTTTGCAGACGCTTGAAAATCAAGCCCCTACTGCACCAGCTAACCCAGCTCCGTCAGTAGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGCTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.877	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	37.631	100	0.383