Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   JG734_RS02855 Genome accession   NZ_AP023065
Coordinates   503548..505347 (-) Length   599 a.a.
NCBI ID   WP_201333525.1    Uniprot ID   A0A7R6VL81
Organism   Nitratiruptor sp. YY09-18     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 498548..510347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JG734_RS02840 (NitYY0918_C0566) - 498632..499009 (-) 378 WP_201333522.1 PleD family two-component system response regulator -
  JG734_RS02845 (NitYY0918_C0567) - 499006..502062 (-) 3057 WP_201333523.1 ATP-binding protein -
  JG734_RS02850 (NitYY0918_C0568) - 502071..503492 (-) 1422 WP_201333524.1 Hpt domain-containing protein -
  JG734_RS02855 (NitYY0918_C0569) uvrC 503548..505347 (-) 1800 WP_201333525.1 excinuclease ABC subunit UvrC Machinery gene
  JG734_RS02860 (NitYY0918_C0570) - 505331..505771 (-) 441 WP_201333526.1 hypothetical protein -
  JG734_RS02865 (NitYY0918_C0572) nadB 505858..507297 (+) 1440 WP_201333527.1 L-aspartate oxidase -
  JG734_RS02870 (NitYY0918_C0573) nhaD 507307..508608 (+) 1302 WP_201333528.1 sodium:proton antiporter NhaD -
  JG734_RS02875 (NitYY0918_C0574) guaA 508619..510169 (+) 1551 WP_201333529.1 glutamine-hydrolyzing GMP synthase -

Sequence

Protein


Download         Length: 599 a.a.        Molecular weight: 69344.62 Da        Isoelectric Point: 10.0110

>NTDB_id=80907 JG734_RS02855 WP_201333525.1 503548..505347(-) (uvrC) [Nitratiruptor sp. YY09-18]
MDLVSKVKNLPDSPGVYQYFDQHGRLLYVGKAKSLKKRVKSYFRMQPFTPAPNLSPRIFKMISETASMEYIVVESENDAL
ILENSLIKQLKPKYNILLRDDKTYPYIYIDLAQEFPRPKITRKVLPGKKIKYFGPFPSAAKDILDSIYEIFPLVQKDSCI
KGKKACLFYQLQKCLAPCEGRVSQEEYTKILKEAIEHIHNKKLLLQKLQERMVSLSGQLRFEEAAQVRDRIERIKNIEIS
SGIDLAKMENLDIYAIATSQDKAAIVRMFMREGKVIASSSNIIRFDPQRGFDIDEAYKRVLLEFYTHETPLTSKTILIAH
PFSEQEQLQKYLSDKFGKKVAILHPQRGEKRRLIELALLNAKEILHKQRNEPSIEEEIQKLFSLHNRPYRIEIFDNSHLQ
GREPVGAMVVYEDGKFDKKSYRHYNLTNKDEYHQMKEMLTRRAQSFAKNPPPDLWIIDGGETLRALAQDIAQSFGVTLDV
IAIAKEKIDAKAHRAKGKAKDILYGESGKIELLPSDKRLQFIQKLRDEAHRFAIEYHRKQRAKHLKTLELFKIKGIAEAK
VQKLLNYFGTFENIKNASIEEIAAVLNEKDAKKIKKAIN

Nucleotide


Download         Length: 1800 bp        

>NTDB_id=80907 JG734_RS02855 WP_201333525.1 503548..505347(-) (uvrC) [Nitratiruptor sp. YY09-18]
ATGGATCTAGTAAGTAAAGTCAAAAATCTTCCTGATTCTCCTGGCGTCTATCAATACTTCGATCAGCATGGAAGACTTTT
GTATGTTGGAAAAGCAAAAAGCCTCAAAAAGCGGGTCAAGAGCTATTTCCGGATGCAGCCATTTACTCCAGCACCTAATC
TCTCACCACGCATTTTCAAAATGATTAGCGAGACTGCCTCAATGGAGTATATTGTCGTAGAGAGCGAGAATGATGCTCTC
ATCTTAGAAAACTCTCTTATAAAACAACTTAAACCAAAATATAATATTCTCTTGCGTGATGACAAAACCTATCCCTATAT
ATATATTGATCTTGCGCAAGAGTTCCCTCGCCCAAAAATTACGCGAAAAGTCCTTCCAGGTAAAAAAATCAAATACTTTG
GCCCCTTTCCAAGTGCTGCGAAAGATATACTAGACTCTATTTATGAAATATTTCCTCTTGTGCAAAAAGATAGCTGCATT
AAAGGTAAAAAAGCATGCCTCTTTTATCAATTGCAAAAGTGCCTTGCCCCATGTGAAGGGCGTGTGAGCCAAGAGGAGTA
TACAAAAATTCTCAAAGAAGCAATTGAACATATTCACAATAAAAAACTGCTTTTACAAAAGCTGCAAGAGAGGATGGTTA
GCCTCTCTGGACAGCTGCGATTTGAAGAGGCTGCACAGGTGCGTGATCGGATTGAGCGCATCAAAAATATAGAAATTTCA
AGTGGTATAGATCTAGCCAAAATGGAAAATCTCGACATCTATGCAATTGCTACTTCACAAGATAAAGCCGCAATTGTACG
TATGTTTATGCGTGAGGGCAAAGTGATAGCAAGTAGCTCAAATATTATTCGTTTCGATCCACAGAGGGGATTTGATATCG
ATGAAGCTTATAAGAGGGTATTGCTCGAGTTTTACACTCACGAAACACCTCTTACTTCCAAAACGATTCTCATAGCACAC
CCCTTTAGTGAACAAGAGCAGCTTCAAAAGTATTTAAGCGACAAATTTGGCAAAAAGGTGGCTATCCTTCATCCACAAAG
AGGTGAAAAGAGGCGTCTTATTGAGTTGGCACTGCTCAATGCCAAAGAGATACTTCATAAGCAAAGAAACGAACCATCTA
TCGAAGAGGAGATTCAAAAGCTCTTCTCTTTGCACAACAGACCTTACCGTATAGAGATATTTGACAACTCCCATCTTCAA
GGAAGAGAGCCTGTGGGTGCGATGGTAGTCTACGAAGATGGAAAATTTGATAAAAAGAGCTATCGCCACTACAATCTCAC
AAACAAAGATGAGTATCATCAAATGAAGGAGATGCTCACTAGACGTGCTCAAAGTTTTGCCAAAAATCCTCCTCCCGATC
TTTGGATCATCGATGGTGGAGAGACTCTTAGAGCTCTTGCACAAGATATTGCTCAAAGTTTTGGCGTCACACTCGATGTC
ATTGCAATTGCAAAAGAGAAAATCGACGCAAAAGCTCATCGCGCCAAAGGAAAAGCCAAAGACATCCTCTATGGAGAAAG
TGGTAAAATCGAGCTGCTACCAAGTGATAAACGCTTGCAATTTATACAAAAGCTGCGAGATGAAGCACACAGATTTGCAA
TAGAATACCATCGCAAACAAAGAGCTAAACATCTCAAAACCCTAGAACTTTTTAAAATCAAAGGAATAGCAGAGGCTAAA
GTGCAAAAACTGCTCAACTATTTTGGAACTTTTGAAAATATTAAAAATGCATCAATTGAAGAAATTGCTGCAGTTTTGAA
CGAAAAAGATGCAAAAAAAATAAAAAAAGCAATCAATTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-95)

UvrB/uvrC motif (UVR)

(204-236)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-534)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7R6VL81

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

53.794

98.998

0.533

Multiple sequence alignment