Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   RMQ61_RS00400 Genome accession   NZ_CP135090
Coordinates   69682..71619 (+) Length   645 a.a.
NCBI ID   WP_313926408.1    Uniprot ID   -
Organism   Streptococcus suis strain ID48908     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 64682..76619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ61_RS00385 (RMQ61_00385) comR 65447..66364 (+) 918 WP_024383080.1 helix-turn-helix domain-containing protein Regulator
  RMQ61_RS00390 (RMQ61_00390) - 66630..67850 (+) 1221 WP_313920896.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  RMQ61_RS00395 (RMQ61_00395) - 68041..69564 (+) 1524 WP_024381981.1 quinol oxidase -
  RMQ61_RS00400 (RMQ61_00400) hexB 69682..71619 (+) 1938 WP_313926408.1 DNA mismatch repair endonuclease MutL Machinery gene
  RMQ61_RS00405 (RMQ61_00405) ruvA 71658..72248 (+) 591 WP_313920898.1 Holliday junction branch migration protein RuvA Machinery gene
  RMQ61_RS00410 (RMQ61_00410) - 72808..73377 (+) 570 WP_313920899.1 DNA-3-methyladenine glycosylase I -
  RMQ61_RS00415 (RMQ61_00415) cinA 73414..74595 (+) 1182 WP_313920900.1 competence/damage-inducible protein A Machinery gene
  RMQ61_RS00420 (RMQ61_00420) recA 74647..75798 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  RMQ61_RS00425 (RMQ61_00425) spx 76034..76432 (+) 399 WP_002939362.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72938.12 Da        Isoelectric Point: 5.1741

>NTDB_id=808987 RMQ61_RS00400 WP_313926408.1 69682..71619(+) (hexB) [Streptococcus suis strain ID48908]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEMAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMKSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=808987 RMQ61_RS00400 WP_313926408.1 69682..71619(+) (hexB) [Streptococcus suis strain ID48908]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAT
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATGGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATTAACGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGATTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCACCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGTATCTACGAGATGTGCGACATGTTGCTTCTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGAAGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.308

100

0.729