Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   JG733_RS07170 Genome accession   NZ_AP023061
Coordinates   1328426..1330252 (+) Length   608 a.a.
NCBI ID   WP_201334376.1    Uniprot ID   A0A7R6ZZK0
Organism   Nitratiruptor sp. YY08-14     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1323426..1335252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JG733_RS07150 (NitYY0814_C1429) guaA 1323608..1325158 (-) 1551 WP_201334372.1 glutamine-hydrolyzing GMP synthase -
  JG733_RS07155 (NitYY0814_C1430) nhaD 1325168..1326469 (-) 1302 WP_201334373.1 sodium:proton antiporter NhaD -
  JG733_RS07160 (NitYY0814_C1431) nadB 1326470..1327915 (-) 1446 WP_201334374.1 L-aspartate oxidase -
  JG733_RS07165 (NitYY0814_C1433) - 1328002..1328442 (+) 441 WP_201334375.1 hypothetical protein -
  JG733_RS07170 (NitYY0814_C1434) uvrC 1328426..1330252 (+) 1827 WP_201334376.1 excinuclease ABC subunit UvrC Machinery gene
  JG733_RS07175 (NitYY0814_C1435) - 1330334..1332163 (+) 1830 WP_201334377.1 Hpt domain-containing protein -
  JG733_RS07180 (NitYY0814_C1436) - 1332160..1332567 (+) 408 WP_201334378.1 sel1 repeat family protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 70565.77 Da        Isoelectric Point: 9.9532

>NTDB_id=80890 JG733_RS07170 WP_201334376.1 1328426..1330252(+) (uvrC) [Nitratiruptor sp. YY08-14]
MQELAKKLRSLPDAPGVYQYFDQNGRLLYVGKAKSLKKRVKSYFRFSPTLTPAPNLSPRIFKMIHETKNLEYIVVESEND
ALILENSLIKQLKPKYNILLRDDKTYPYLYVDFNEIFPRIKLTRKVVQGSNIRYFGPFPSAAKEILDSLYELFPLVQKES
CIKGKKACLFYQMKRCLAPCEGYVTPKEYAQILDKAIFHLKDKQRLIEKLQNKMHEYAEQLRFEEAASLRDRIKKIESVQ
IQSGIDFAKMENLDIFAIEENEKQAVLVRLFMREGKVISSSSTLYRIDKEKGFDKSEAYKRALLEFYQTQTPLTASRIIV
AHDFSERDSIQNYLSEKFGKKITVQHPLRGEKRKIANLALLNAQELLKKSTTQNQIEDVIKTYFQLRHSPYRIEAFDNSH
ISGSNPVGAMVVYENGKFVKSDYRHYSLHHKDEYAQMKELLTRRCESFASNPPPDLWLIDGGETLRQLAEDILQSHGVVI
DVIAIAKEKSDAKTHRAKGKAKDILYSSKGIHKLSPADEKLLFFQKIRDEVHRFALNFHRKKRQKESMIVELLKVKGIGE
GKLKKLLRFYGSFEKIKEGSFEELQHLVGEKAAQKILEHLSKHDLNLL

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=80890 JG733_RS07170 WP_201334376.1 1328426..1330252(+) (uvrC) [Nitratiruptor sp. YY08-14]
ATGCAAGAACTCGCTAAAAAATTACGTTCTTTACCGGATGCTCCCGGTGTGTATCAATATTTTGATCAAAATGGAAGGCT
GCTGTATGTCGGAAAGGCGAAAAGTCTCAAAAAAAGGGTCAAAAGCTACTTTCGATTTTCGCCTACGCTAACCCCTGCGC
CAAATCTCTCTCCAAGAATCTTTAAAATGATACATGAAACAAAAAATTTGGAGTATATTGTCGTAGAGAGTGAGAACGAT
GCACTCATTTTGGAAAACTCGCTTATCAAACAACTCAAACCAAAATACAATATTCTACTTCGAGACGATAAAACATATCC
CTACCTGTATGTAGATTTCAACGAAATATTTCCAAGAATCAAACTGACAAGAAAAGTTGTCCAAGGAAGCAATATCAGAT
ATTTTGGCCCTTTTCCATCTGCAGCAAAAGAGATTTTGGACTCTTTGTACGAACTTTTTCCTCTCGTTCAAAAAGAGAGC
TGTATCAAAGGAAAAAAAGCATGCCTTTTTTATCAGATGAAAAGGTGTTTGGCACCTTGTGAAGGCTATGTCACTCCAAA
GGAGTATGCACAAATCTTAGATAAAGCGATTTTTCATCTCAAGGATAAACAAAGACTCATCGAAAAACTGCAAAATAAGA
TGCACGAATATGCCGAACAGCTCCGTTTTGAAGAAGCAGCCAGTCTTAGAGACAGAATAAAAAAAATCGAATCCGTACAG
ATTCAAAGCGGTATCGATTTTGCAAAAATGGAAAATCTCGATATTTTTGCGATCGAAGAGAATGAAAAGCAGGCGGTACT
TGTACGGCTTTTTATGCGGGAAGGAAAAGTCATTTCAAGCAGTTCGACACTCTACCGTATCGACAAAGAGAAAGGATTTG
ATAAATCCGAAGCGTACAAAAGAGCTCTTTTGGAGTTTTATCAAACCCAAACACCTCTCACAGCATCTCGGATCATTGTG
GCGCACGATTTTAGCGAAAGAGACTCTATCCAAAACTATTTAAGTGAAAAATTTGGTAAAAAAATCACTGTTCAACACCC
ATTGCGAGGAGAAAAACGAAAAATAGCCAATTTGGCGCTGCTCAACGCTCAAGAATTATTGAAAAAGAGTACCACACAAA
ACCAAATTGAAGATGTGATCAAAACCTATTTTCAGCTTCGACATTCTCCATACAGAATCGAAGCATTTGACAACTCTCAC
ATCAGCGGATCCAATCCTGTCGGTGCAATGGTAGTATACGAAAACGGGAAATTTGTAAAATCCGATTATAGGCACTATTC
GCTCCACCACAAAGATGAGTATGCACAGATGAAAGAACTGCTGACACGAAGATGTGAGAGTTTTGCAAGCAATCCTCCAC
CCGATCTATGGCTGATTGACGGCGGCGAAACACTGCGTCAGCTTGCCGAAGATATTCTGCAAAGCCACGGTGTCGTTATT
GACGTTATTGCAATAGCAAAAGAAAAATCGGATGCGAAGACACACCGTGCCAAAGGAAAAGCAAAAGATATTCTCTATAG
CAGTAAAGGAATCCACAAGCTTTCACCTGCCGATGAAAAGTTGCTCTTTTTTCAAAAAATCAGAGACGAAGTCCACCGTT
TTGCTCTAAATTTTCATAGAAAAAAACGACAAAAAGAGTCGATGATTGTTGAACTGTTAAAAGTGAAAGGTATTGGTGAG
GGGAAACTGAAAAAGTTGCTTCGTTTTTATGGTTCATTCGAAAAGATCAAAGAAGGCAGCTTTGAAGAATTGCAACATCT
TGTCGGGGAAAAAGCAGCCCAAAAGATTTTGGAACATCTATCTAAGCATGATTTAAATTTGTTATGA

Domains

Predicted by InterproScan.

Helix-hairpin-helix domain (HHH_5)

(551-601)

UvrB/uvrC motif (UVR)

(205-238)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-535)

GIY-YIG catalytic domain (GIY-YIG)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7R6ZZK0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.085

96.875

0.485

Multiple sequence alignment