Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   P4831_RS12240 Genome accession   NZ_CP120842
Coordinates   2357178..2358206 (-) Length   342 a.a.
NCBI ID   WP_010906347.1    Uniprot ID   A0AAP4JQE3
Organism   Lactococcus lactis strain ZFM559     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2352178..2363206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P4831_RS12210 - 2352464..2352961 (-) 498 WP_021214977.1 nitroreductase family protein -
  P4831_RS12215 - 2352948..2353157 (-) 210 WP_003132661.1 hypothetical protein -
  P4831_RS12220 - 2353154..2353981 (-) 828 WP_010906344.1 radical SAM protein -
  P4831_RS12225 - 2353974..2356097 (-) 2124 WP_023164665.1 radical SAM protein -
  P4831_RS12230 - 2356200..2356811 (-) 612 WP_023164666.1 hypothetical protein -
  P4831_RS12235 - 2356827..2357057 (-) 231 WP_023164667.1 XRE family transcriptional regulator -
  P4831_RS12240 sepM 2357178..2358206 (-) 1029 WP_010906347.1 SepM family pheromone-processing serine protease Regulator
  P4831_RS12245 coaD 2358193..2358690 (-) 498 WP_277812531.1 pantetheine-phosphate adenylyltransferase -
  P4831_RS12250 rsmD 2358738..2359277 (-) 540 WP_015427191.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  P4831_RS12255 - 2359448..2360668 (-) 1221 WP_003132654.1 MFS transporter -
  P4831_RS12260 lmrP 2360751..2361977 (-) 1227 WP_023164669.1 multidrug efflux MFS transporter LmrP -
  P4831_RS12265 - 2362165..2362659 (+) 495 WP_017865181.1 RNA polymerase sigma factor -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37379.98 Da        Isoelectric Point: 9.9183

>NTDB_id=808804 P4831_RS12240 WP_010906347.1 2357178..2358206(-) (sepM) [Lactococcus lactis strain ZFM559]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=808804 P4831_RS12240 WP_010906347.1 2357178..2358206(-) (sepM) [Lactococcus lactis strain ZFM559]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491