Detailed information NTG0808522

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RMQ62_RS06170
• Genome accession: NZ_CP135065
• Coordinates: 1253541..1256081 (+)
• Length: 846 a.a.
• NCBI ID: WP_313680535.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ID24665
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1248541..1261081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMQ62_RS06145 (RMQ62_06145)	-	1249328..1249510 (-)	183	WP_313741736.1	hypothetical protein	-
RMQ62_RS06150 (RMQ62_06150)	-	1249622..1250143 (+)	522	WP_012775401.1	hypothetical protein	-
RMQ62_RS06155 (RMQ62_06155)	-	1250197..1251111 (-)	915	WP_015647551.1	SH3 domain-containing protein	-
RMQ62_RS06160 (RMQ62_06160)	argS	1251291..1252979 (-)	1689	WP_015647550.1	arginine--tRNA ligase	-
RMQ62_RS06165 (RMQ62_06165)	argR	1253086..1253526 (+)	441	WP_002937036.1	arginine repressor	-
RMQ62_RS06170 (RMQ62_06170)	hexA	1253541..1256081 (+)	2541	WP_313680535.1	DNA mismatch repair protein MutS	Machinery gene
RMQ62_RS06175 (RMQ62_06175)	-	1256320..1256493 (+)	174	WP_002941962.1	hypothetical protein	-
RMQ62_RS06180 (RMQ62_06180)	-	1256606..1257292 (+)	687	WP_014638811.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
RMQ62_RS06185 (RMQ62_06185)	-	1257325..1258176 (+)	852	WP_253218631.1	amino acid ABC transporter substrate-binding protein	-
RMQ62_RS06190 (RMQ62_06190)	-	1258362..1259165 (+)	804	WP_024407716.1	amino acid ABC transporter permease	-
RMQ62_RS06195 (RMQ62_06195)	-	1259165..1259908 (+)	744	WP_313680533.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 94998.56 Da
• Isoelectric Point: 4.8485

>NTDB_id=808522 RMQ62_RS06170 WP_313680535.1 1253541..1256081(+) (hexA) [Streptococcus suis strain ID24665]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLIAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPSHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDCGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAALPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLERADRILQTLENQAPTAPANLALSVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMRVAELKKKL

Nucleotide

• Length: 2541 bp

>NTDB_id=808522 RMQ62_RS06170 WP_313680535.1 1253541..1256081(+) (hexA) [Streptococcus suis strain ID24665]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAACAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGAGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTAGTCATCGGCTACGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGTCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGTCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGATAGCTGGATTGGACCCAATTCCAGAACTGCATGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACGGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCATCTGGTATCAATAATCTCAAGATTGATT
ACAACAAAAAAGACGGCTACTATTTCCATGTGACCAATTCCAATCTGGGCAATGTGCCTAGTCATTTCTTCCGTAAGGCG
ACCTTGAAAAACTCGGAACGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCAGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAATTGACCATTGACTGTGGTCGTCATGCAGTGGTGGAGAAAGTCATGGGCAAGCAGACTTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACAGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGCATTGCCGATTTTCGATGCT
ATTTTCACTCGTATTGGGGCGGCAGACGACTTGGTCAGCGGTCAATCTACCTTTATGGTTGAGATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGACGAGCTGGGGCGGGGAACGGCCACCTATGATGGTATGG
CTCTGGCTCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCTAAGACTCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCACGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTCGCTAAGATTGCGGGAATGCCAGAGGAGTTAT
TGGAGCGGGCGGATAGGATTTTGCAGACACTTGAAAACCAAGCCCCTACTGCACCAGCTAACCTAGCTCTGTCAGTTGTG
GAAGAGCCGTCTGGTCAAATTGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGCAAAACTGGACAT
CTACAATATGACCCCTATGGAAGTCATGATGAGGGTGGCAGAATTGAAGAAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.498	100	0.746
mutS	Pseudomonas stutzeri strain ATCC 17587	37.193	100	0.376