Detailed information NTG0808349

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: RND68_RS10935
• Genome accession: NZ_CP134882
• Coordinates: 2128241..2130226 (-)
• Length: 661 a.a.
• NCBI ID: WP_000229253.1
• Uniprot ID: A0A0H2XGZ8
• Organism: Staphylococcus aureus strain 10-5-1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2123241..2135226

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RND68_RS10925 (RND68_10925)	hprK	2123844..2124776 (-)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
RND68_RS10930 (RND68_10930)	uvrA	2125387..2128233 (-)	2847	WP_000662687.1	excinuclease ABC subunit UvrA	Machinery gene
RND68_RS10935 (RND68_10935)	uvrB	2128241..2130226 (-)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
RND68_RS10940 (RND68_10940)	-	2130495..2130731 (-)	237	WP_000638419.1	CsbA family protein	-
RND68_RS10945 (RND68_10945)	-	2130728..2131378 (-)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
RND68_RS10950 (RND68_10950)	-	2131552..2132391 (-)	840	WP_000749385.1	CHAP domain-containing protein	-
RND68_RS10960 (RND68_10960)	-	2134445..2134543 (-)	99	WP_001791369.1	hypothetical protein	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 76648.34 Da
• Isoelectric Point: 5.0538

>NTDB_id=808349 RND68_RS10935 WP_000229253.1 2128241..2130226(-) (uvrB) [Staphylococcus aureus strain 10-5-1]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide

• Length: 1986 bp

>NTDB_id=808349 RND68_RS10935 WP_000229253.1 2128241..2130226(-) (uvrB) [Staphylococcus aureus strain 10-5-1]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTTGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATTCGAGAAGTTAACTACCTAACTGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGATTTAGATTACCGAGTGCAT
TAGATAACCGTCCTCTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGGGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (434-546)

• Ultra-violet resistance protein B (UvrB) (553-594)

• Type III restriction enzyme, res subunit (ResIII) (14-140)

• UvrB/uvrC motif (UVR) (626-659)

• UvrB interaction domain (UvrB_inter) (161-251)

3D structure

• AlphaFold DB: A0A0H2XGZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae TIGR4	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae D39	67.534	98.79	0.667