Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HXS61_RS01440 Genome accession   NZ_AP023046
Coordinates   276467..277726 (+) Length   419 a.a.
NCBI ID   WP_034375723.1    Uniprot ID   A0A6J4CVY0
Organism   Helicobacter suis strain NHP19-4022     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 271467..282726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HXS61_RS01430 (NHP194022_02940) - 273861..274964 (+) 1104 WP_176486377.1 VirB8/TrbF family protein -
  HXS61_RS01435 (NHP194022_02950) - 274948..276477 (+) 1530 WP_006564108.1 TrbG/VirB9 family P-type conjugative transfer protein -
  HXS61_RS01440 (NHP194022_02960) comB10 276467..277726 (+) 1260 WP_034375723.1 DNA type IV secretion system protein ComB10 Machinery gene
  HXS61_RS01445 (NHP194022_02970) - 277746..279887 (+) 2142 WP_232087234.1 collagen-like protein -
  HXS61_RS01450 (NHP194022_02980) - 279907..280878 (+) 972 WP_104683451.1 hypothetical protein -
  HXS61_RS01455 (NHP194022_02990) - 280890..281165 (+) 276 WP_050782209.1 hypothetical protein -
  HXS61_RS01460 (NHP194022_03000) - 281330..282412 (+) 1083 WP_073193814.1 RNA-guided endonuclease TnpB family protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 46535.81 Da        Isoelectric Point: 10.1397

>NTDB_id=80805 HXS61_RS01440 WP_034375723.1 276467..277726(+) (comB10) [Helicobacter suis strain NHP19-4022]
MDANTKKWLKRGGIVLGGALGLFVLAMVVDKNTGKSKEEILELEESTYPLSDYFFVNGKKKDQPQSLPQIETHQHNTKKD
YNTINKELEAQNKALEKALESAKQEAKKLPQVVVLKNTETPKSIGSVATPQPVAPIVPPRTRRLTKEQLELLNSRMSPFE
PLKDAPKAEIDYGVDSFENLKAQDKGTNENKLLRTITADKMIPAFLITPISSQIAGKVTAQVETDIFANMGRAVLIPKGS
KVIGYYNNNNKIGEYRLNIAWTRIITPQGINIMLTNARGVDVKGYNGLIGKVIARNFSKYGMPLLTSTLSNGLLIALTSA
LANRQNKAGVGNPFFGDYLLMQLTRNTGMSLNQIVGQILADKARINPIIIIREGSRVFISPNLDIFIPKPRHGEVLAQFF
KEKKPVVKSQEESYEENEF

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=80805 HXS61_RS01440 WP_034375723.1 276467..277726(+) (comB10) [Helicobacter suis strain NHP19-4022]
ATGGATGCTAACACCAAGAAATGGCTCAAAAGAGGAGGGATTGTGCTGGGGGGAGCTTTAGGTTTGTTTGTGCTGGCTAT
GGTGGTGGATAAGAACACAGGAAAGTCTAAAGAAGAAATCCTTGAGTTAGAGGAAAGCACCTATCCTTTGAGTGATTATT
TTTTTGTCAATGGCAAGAAAAAAGACCAGCCCCAGAGTTTGCCACAGATAGAAACACACCAGCACAACACCAAAAAAGAC
TACAACACCATCAACAAGGAGCTAGAAGCGCAAAACAAAGCCCTAGAGAAAGCCTTAGAGAGCGCCAAGCAAGAAGCTAA
GAAACTTCCACAAGTGGTGGTGCTTAAAAACACAGAGACACCCAAGTCTATTGGGAGTGTGGCAACACCCCAGCCTGTTG
CTCCTATTGTGCCCCCACGCACCAGAAGACTCACCAAAGAGCAATTAGAGCTCTTAAACTCTAGAATGAGCCCCTTTGAG
CCCCTCAAAGATGCGCCCAAAGCAGAGATTGACTATGGAGTAGATAGCTTTGAAAATCTCAAAGCCCAAGATAAAGGTAC
AAATGAGAATAAGCTCTTAAGAACGATCACCGCTGATAAGATGATTCCAGCCTTTCTGATCACGCCCATCTCTAGCCAAA
TTGCGGGCAAGGTTACTGCACAGGTGGAGACAGATATTTTTGCCAATATGGGCAGGGCTGTGCTCATCCCTAAGGGCTCA
AAGGTTATTGGCTATTACAATAACAACAATAAGATAGGTGAATACCGCCTCAACATTGCATGGACGCGCATTATCACACC
TCAAGGCATTAATATCATGCTCACCAATGCTAGAGGCGTAGATGTGAAGGGCTATAATGGGTTGATTGGTAAGGTCATTG
CCCGTAACTTCTCTAAATATGGCATGCCCTTACTCACCTCCACTCTCTCTAATGGCTTGCTCATCGCGCTCACCTCTGCT
CTAGCTAATAGACAGAATAAGGCAGGGGTGGGCAACCCTTTTTTTGGGGACTATCTCTTGATGCAACTGACCCGCAACAC
AGGGATGAGCCTCAATCAGATCGTAGGACAAATCCTAGCAGACAAAGCCCGTATCAATCCTATTATCATCATTAGAGAAG
GAAGCCGTGTTTTTATCTCCCCTAATTTAGACATCTTCATCCCTAAGCCTAGGCATGGGGAAGTCCTCGCACAATTTTTT
AAAGAGAAAAAGCCCGTTGTTAAATCACAGGAGGAAAGCTATGAGGAAAATGAGTTTTAG

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(195-385)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6J4CVY0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

53.563

97.136

0.52

Multiple sequence alignment