Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   P4B11_RS13945 Genome accession   NZ_CP120652
Coordinates   2790263..2790979 (-) Length   238 a.a.
NCBI ID   WP_064128191.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 205M     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2785263..2795979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P4B11_RS13925 (P4B11_13950) - 2786356..2787306 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  P4B11_RS13930 (P4B11_13955) - 2787455..2788939 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  P4B11_RS13935 (P4B11_13960) - 2788936..2789894 (+) 959 Protein_2707 carbohydrate kinase -
  P4B11_RS13940 (P4B11_13965) - 2790082..2790191 (-) 110 Protein_2708 hypothetical protein -
  P4B11_RS13945 (P4B11_13970) agrA 2790263..2790979 (-) 717 WP_064128191.1 quorum-sensing response regulator AgrA Regulator
  P4B11_RS13950 (P4B11_13975) agrC 2790998..2792281 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  P4B11_RS13955 (P4B11_13980) agrD 2792311..2792454 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  P4B11_RS13960 (P4B11_13985) - 2792457..2793020 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  P4B11_RS13965 hld 2793310..2793390 (+) 81 WP_000046022.1 delta-hemolysin -
  P4B11_RS13970 (P4B11_13995) - 2793990..2794775 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  P4B11_RS13975 (P4B11_14000) - 2795136..2795762 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.95 Da        Isoelectric Point: 6.0927

>NTDB_id=807489 P4B11_RS13945 WP_064128191.1 2790263..2790979(-) (agrA) [Staphylococcus aureus strain 205M]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIVHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=807489 P4B11_RS13945 WP_064128191.1 2790263..2790979(-) (agrA) [Staphylococcus aureus strain 205M]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGTCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996