Detailed information NTG0080734

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HZ307_RS09815
• Genome accession: NZ_AP023034
• Coordinates: 1993912..1994955 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TPS3156
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1988912..1999955

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HZ307_RS09785 (USA300LVJ_18300)	-	1989330..1990586 (-)	1257	WP_001795438.1	aminopeptidase	-
HZ307_RS09790 (USA300LVJ_18310)	-	1990589..1990789 (-)	201	WP_000180461.1	DUF1128 family protein	-
HZ307_RS09795 (USA300LVJ_18320)	-	1990936..1991400 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
HZ307_RS09800 (USA300LVJ_18330)	-	1991407..1991682 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HZ307_RS09805 (USA300LVJ_18340)	-	1991960..1993177 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
HZ307_RS09810 (USA300LVJ_18350)	vraR	1993293..1993922 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
HZ307_RS09815 (USA300LVJ_18360)	vraS	1993912..1994955 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HZ307_RS09820 (USA300LVJ_18370)	liaF	1994952..1995653 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HZ307_RS09825 (USA300LVJ_18380)	-	1995668..1996054 (-)	387	WP_001110179.1	hypothetical protein	-
HZ307_RS09830 (USA300LVJ_18390)	map	1996271..1997029 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HZ307_RS09835 (USA300LVJ_18400)	-	1997557..1998543 (+)	987	WP_000999713.1	FUSC family protein	-
HZ307_RS09840 (USA300LVJ_18410)	-	1999033..1999446 (-)	414	WP_001549145.1	hypothetical protein	-
HZ307_RS09845	-	1999475..1999585 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=80734 HZ307_RS09815 WP_001017131.1 1993912..1994955(-) (vraS) [Staphylococcus aureus strain TPS3156]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=80734 HZ307_RS09815 WP_001017131.1 1993912..1994955(-) (vraS) [Staphylococcus aureus strain TPS3156]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1