Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   HZ307_RS07870 Genome accession   NZ_AP023034
Coordinates   1623710..1624684 (-) Length   324 a.a.
NCBI ID   WP_047335164.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TPS3156     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1618710..1629684
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HZ307_RS07830 (USA300LVJ_14970) gcvT 1619211..1620302 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  HZ307_RS07835 (USA300LVJ_14980) - 1620461..1620985 (-) 525 WP_001015117.1 shikimate kinase -
  HZ307_RS07840 - 1620975..1621121 (-) 147 WP_001789879.1 hypothetical protein -
  HZ307_RS07845 (USA300LVJ_14990) comGF 1621218..1621715 (-) 498 WP_001789864.1 competence type IV pilus minor pilin ComGF Machinery gene
  HZ307_RS07850 (USA300LVJ_15000) comGE 1621633..1621932 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  HZ307_RS07855 (USA300LVJ_15010) comGD 1621919..1622365 (-) 447 WP_001791635.1 competence type IV pilus minor pilin ComGD Machinery gene
  HZ307_RS07860 (USA300LVJ_15020) comGC 1622343..1622654 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  HZ307_RS07865 (USA300LVJ_15030) comGB 1622668..1623738 (-) 1071 WP_000775708.1 competence type IV pilus assembly protein ComGB Machinery gene
  HZ307_RS07870 (USA300LVJ_15040) comGA 1623710..1624684 (-) 975 WP_047335164.1 competence type IV pilus ATPase ComGA Machinery gene
  HZ307_RS07875 (USA300LVJ_15050) - 1624736..1625359 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  HZ307_RS07880 (USA300LVJ_15060) - 1625356..1625685 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  HZ307_RS07885 (USA300LVJ_15070) - 1625685..1626671 (-) 987 WP_000161314.1 ROK family glucokinase -
  HZ307_RS07890 (USA300LVJ_15080) - 1626668..1626871 (-) 204 WP_000087561.1 YqgQ family protein -
  HZ307_RS07895 (USA300LVJ_15090) - 1626852..1628315 (-) 1464 WP_001017867.1 rhomboid family protein -
  HZ307_RS07900 (USA300LVJ_15100) - 1628327..1628866 (-) 540 WP_178890274.1 5-formyltetrahydrofolate cyclo-ligase -
  HZ307_RS07905 (USA300LVJ_15110) rpmG 1629075..1629224 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36850.99 Da        Isoelectric Point: 9.0399

>NTDB_id=80722 HZ307_RS07870 WP_047335164.1 1623710..1624684(-) (comGA) [Staphylococcus aureus strain TPS3156]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSVYQKLLVYMKFQAGLDVSTQQVAQSGRYSYLF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQPQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
HKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=80722 HZ307_RS07870 WP_047335164.1 1623710..1624684(-) (comGA) [Staphylococcus aureus strain TPS3156]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCGTTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCTTTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACCACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATAAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
CATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

98.765

100

0.988
  comGA Staphylococcus aureus N315

98.765

100

0.988

Multiple sequence alignment