Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QN337_RS00425 Genome accession   NZ_CP134688
Coordinates   75121..75762 (+) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain MA07     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 70121..80762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN337_RS00405 (QN337_00405) - 70566..71303 (+) 738 WP_000406231.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QN337_RS00410 (QN337_00410) pknB 71303..73258 (+) 1956 WP_000614570.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QN337_RS00415 (QN337_00415) liaF 73417..74112 (+) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  QN337_RS00420 (QN337_00420) - 74109..75128 (+) 1020 WP_000716170.1 sensor histidine kinase -
  QN337_RS00425 (QN337_00425) vraR 75121..75762 (+) 642 WP_000357891.1 response regulator transcription factor Regulator
  QN337_RS00430 (QN337_00430) - 75804..77204 (+) 1401 WP_000339135.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  QN337_RS00435 (QN337_00435) - 77206..77562 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  QN337_RS00440 (QN337_00440) - 77609..78385 (-) 777 WP_000180537.1 glycyl-radical enzyme activating protein -
  QN337_RS00445 (QN337_00445) - 78506..79261 (+) 756 WP_001080746.1 DeoR/GlpR family DNA-binding transcription regulator -
  QN337_RS00450 (QN337_00450) - 79380..80363 (+) 984 WP_000764455.1 sugar-binding transcriptional regulator -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=807186 QN337_RS00425 WP_000357891.1 75121..75762(+) (vraR) [Streptococcus agalactiae strain MA07]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=807186 QN337_RS00425 WP_000357891.1 75121..75762(+) (vraR) [Streptococcus agalactiae strain MA07]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAGGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGACGTTGTTG
TTATGGACTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTATTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTAGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394