Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   RL451_RS06450 Genome accession   NZ_CP134617
Coordinates   1294146..1294820 (-) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain IPLA16     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1289146..1299820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL451_RS06435 (RL451_06435) vraG 1290329..1292218 (-) 1890 WP_000143619.1 ABC transporter permease VraG -
  RL451_RS06440 (RL451_06440) vraF 1292208..1292969 (-) 762 WP_043854684.1 ABC transporter ATP-binding protein VraF -
  RL451_RS06445 (RL451_06445) graS 1293113..1294153 (-) 1041 WP_001061256.1 histidine kinase GraS/ApsS -
  RL451_RS06450 (RL451_06450) braR 1294146..1294820 (-) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  RL451_RS06455 (RL451_06455) graX 1294836..1295759 (-) 924 WP_000802955.1 auxiliary protein GraX/ApsX -
  RL451_RS06460 (RL451_06460) - 1295872..1296378 (+) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  RL451_RS06465 (RL451_06465) - 1296587..1297015 (-) 429 WP_000198504.1 hypothetical protein -
  RL451_RS06470 (RL451_06470) - 1297344..1298387 (-) 1044 WP_001030771.1 alpha/beta hydrolase -
  RL451_RS06475 (RL451_06475) - 1298538..1299605 (-) 1068 WP_331385854.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=806982 RL451_RS06450 WP_001166500.1 1294146..1294820(-) (braR) [Staphylococcus aureus strain IPLA16]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=806982 RL451_RS06450 WP_001166500.1 1294146..1294820(-) (braR) [Staphylococcus aureus strain IPLA16]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTTGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAGCCTTTTTATACAAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTCCTGTCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397