Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RLT58_RS32370 Genome accession   NZ_CP134609
Coordinates   7307642..7308307 (+) Length   221 a.a.
NCBI ID   WP_311313904.1    Uniprot ID   -
Organism   Streptomyces sp. ITFR-16     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7302642..7313307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RLT58_RS32350 (RLT58_32350) - 7303614..7304828 (+) 1215 WP_311313900.1 geranylgeranyl reductase family protein -
  RLT58_RS32355 (RLT58_32355) - 7304877..7305338 (-) 462 WP_311313901.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  RLT58_RS32360 (RLT58_32360) - 7305482..7306207 (+) 726 WP_311313902.1 TetR/AcrR family transcriptional regulator -
  RLT58_RS32365 (RLT58_32365) - 7306317..7307645 (+) 1329 WP_399131983.1 sensor histidine kinase -
  RLT58_RS32370 (RLT58_32370) vraR 7307642..7308307 (+) 666 WP_311313904.1 response regulator transcription factor Regulator
  RLT58_RS32375 (RLT58_32375) - 7308268..7308579 (-) 312 WP_311313905.1 DUF6332 family protein -
  RLT58_RS32380 (RLT58_32380) - 7308645..7309400 (-) 756 WP_311313906.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  RLT58_RS32385 (RLT58_32385) - 7309422..7309793 (-) 372 WP_311313907.1 SCO4225 family membrane protein -
  RLT58_RS32390 (RLT58_32390) - 7309872..7310990 (-) 1119 WP_311314720.1 MFS transporter -
  RLT58_RS32395 (RLT58_32395) - 7311231..7312445 (+) 1215 WP_311313908.1 ROK family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23845.62 Da        Isoelectric Point: 5.0193

>NTDB_id=806846 RLT58_RS32370 WP_311313904.1 7307642..7308307(+) (vraR) [Streptomyces sp. ITFR-16]
MIRVLLADDQLLVRAGFRALLDAQPDIGVAGEAADGEEAVRLVRELRPDAVLMDIRMPRLDGLAATRAITGDPALHDVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVAGDALLSPGVTRRLIAEFAARSKEPAAASGLSELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=806846 RLT58_RS32370 WP_311313904.1 7307642..7308307(+) (vraR) [Streptomyces sp. ITFR-16]
GTGATCCGCGTACTGCTCGCCGATGACCAGCTGCTGGTCAGGGCGGGATTCAGGGCCCTGCTGGACGCCCAGCCGGACAT
CGGGGTGGCGGGCGAGGCGGCCGACGGGGAGGAGGCCGTCCGTCTGGTGCGCGAACTGCGGCCGGACGCCGTCCTGATGG
ACATCCGGATGCCGCGCCTCGACGGACTCGCCGCGACCCGCGCCATCACCGGGGACCCCGCGCTCCACGACGTGAAGGTG
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAGCCGGAAGAACTGCTGCGGGCCGTCCGGGCGGTGGTGGCGGGAGACGCCCTGCTCTCCCCGGGGGTCACGCGCC
GCCTCATCGCCGAGTTCGCGGCCCGCTCCAAGGAGCCGGCCGCCGCGTCCGGGCTGAGCGAACTGACCGAACGGGAGCGG
GAGGTGATGGCCCTGGTCGGCATCGGCCTCTCCAACGAGGAGATCGCCCGCCGCCTCGTCGTCAGCCCGCTCACCGCCAA
GACCCATGTCAGCCGCACCATGGTGAAACTCGGCGCCCGCGACCGGGCCCAACTGGTCGTCCTGGCCTATGAGTCGGGAC
TCGTCCGCCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.674

97.285

0.367