Detailed information NTG0805810

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLUC147_RS11365
• Genome accession: NZ_CP120473
• Coordinates: 2233833..2234864 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain UC147
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2228833..2239864

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC147_RS11340 (LLUC147_11370)	-	2230037..2230534 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLUC147_RS11345 (LLUC147_11375)	-	2230521..2230730 (-)	210	WP_011677212.1	hypothetical protein	-
LLUC147_RS11350 (LLUC147_11380)	-	2231018..2231908 (+)	891	WP_064305155.1	IS982-like element IS982B family transposase	-
LLUC147_RS11355 (LLUC147_11385)	kwcM	2232053..2233333 (-)	1281	WP_396425240.1	KxxxW cyclic peptide radical SAM maturase	-
LLUC147_RS11360 (LLUC147_11390)	-	2233401..2233514 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLUC147_RS11365 (LLUC147_11395)	sepM	2233833..2234864 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLUC147_RS11370 (LLUC147_11400)	coaD	2234848..2235348 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLUC147_RS11375 (LLUC147_11405)	rsmD	2235396..2235935 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLUC147_RS11380 (LLUC147_11410)	-	2236106..2237326 (-)	1221	WP_134047487.1	MFS transporter	-
LLUC147_RS11385 (LLUC147_11415)	lmrP	2237410..2238636 (-)	1227	Protein_2214	multidrug efflux MFS transporter LmrP	-
LLUC147_RS11390 (LLUC147_11420)	-	2238824..2239318 (+)	495	WP_021164846.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=805810 LLUC147_RS11365 WP_011677213.1 2233833..2234864(-) (sepM) [Lactococcus cremoris strain UC147]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=805810 LLUC147_RS11365 WP_011677213.1 2233833..2234864(-) (sepM) [Lactococcus cremoris strain UC147]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49