Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | P5W76_RS07815 | Genome accession | NZ_CP120425 |
| Coordinates | 1649515..1650861 (+) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus epidermidis strain 25DSE01 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 1623320..1664317 | 1649515..1650861 | within | 0 |
Gene organization within MGE regions
Location: 1623320..1664317
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P5W76_RS07705 | - | 1623320..1625005 (-) | 1686 | WP_032603677.1 | recombinase family protein | - |
| P5W76_RS07710 | - | 1625232..1626839 (-) | 1608 | WP_002504273.1 | DUF5906 domain-containing protein | - |
| P5W76_RS07715 | - | 1626832..1627206 (-) | 375 | WP_203352136.1 | hypothetical protein | - |
| P5W76_RS07720 | - | 1627196..1628332 (-) | 1137 | WP_277369469.1 | DNA polymerase | - |
| P5W76_RS07725 | - | 1628421..1628774 (-) | 354 | WP_002504077.1 | hypothetical protein | - |
| P5W76_RS07730 | - | 1628981..1630843 (-) | 1863 | WP_002504078.1 | DUF6038 family protein | - |
| P5W76_RS07735 | - | 1631458..1634139 (+) | 2682 | WP_002484615.1 | MMPL family transporter | - |
| P5W76_RS07740 | - | 1634163..1635107 (+) | 945 | WP_002484621.1 | glycine betaine ABC transporter substrate-binding protein | - |
| P5W76_RS07745 | - | 1635457..1636026 (+) | 570 | WP_002504079.1 | TetR/AcrR family transcriptional regulator | - |
| P5W76_RS07750 | - | 1636237..1636911 (+) | 675 | Protein_1523 | IS6 family transposase | - |
| P5W76_RS07755 | lpdA | 1637128..1638549 (-) | 1422 | WP_002504088.1 | dihydrolipoyl dehydrogenase | - |
| P5W76_RS07760 | - | 1638731..1641139 (-) | 2409 | WP_002504087.1 | heavy metal translocating P-type ATPase | - |
| P5W76_RS07765 | - | 1641398..1642093 (-) | 696 | WP_227532804.1 | ZIP family metal transporter | - |
| P5W76_RS07770 | - | 1642419..1642820 (-) | 402 | WP_002454665.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| P5W76_RS07775 | lspA | 1642982..1643434 (+) | 453 | WP_161799966.1 | signal peptidase II | - |
| P5W76_RS07780 | - | 1643462..1644136 (-) | 675 | Protein_1529 | IS6 family transposase | - |
| P5W76_RS07785 | - | 1644180..1644849 (+) | 670 | Protein_1530 | transposase | - |
| P5W76_RS07790 | - | 1645074..1645646 (-) | 573 | WP_000489177.1 | ADP-ribosyltransferase | - |
| P5W76_RS07795 | - | 1645699..1646748 (-) | 1050 | WP_000613217.1 | hypothetical protein | - |
| P5W76_RS07800 | - | 1646886..1647170 (+) | 285 | WP_000659554.1 | DUF1413 domain-containing protein | - |
| P5W76_RS07805 | - | 1647170..1648957 (+) | 1788 | WP_000181743.1 | DUF927 domain-containing protein | - |
| P5W76_RS07810 | - | 1649047..1649322 (+) | 276 | WP_001791132.1 | hypothetical protein | - |
| P5W76_RS07815 | ccrA | 1649515..1650861 (+) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
| P5W76_RS07820 | ccrB | 1650882..1652510 (+) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| P5W76_RS07825 | - | 1652981..1653331 (+) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| P5W76_RS07830 | - | 1653416..1653727 (+) | 312 | WP_000833212.1 | DUF960 family protein | - |
| P5W76_RS07835 | - | 1653746..1654267 (+) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| P5W76_RS07840 | - | 1654269..1654475 (+) | 207 | WP_001077283.1 | hypothetical protein | - |
| P5W76_RS07845 | - | 1654573..1654833 (+) | 261 | Protein_1542 | JAB domain-containing protein | - |
| P5W76_RS07850 | - | 1654887..1655525 (-) | 639 | Protein_1543 | sulfite exporter TauE/SafE family protein | - |
| P5W76_RS07855 | cstR | 1655525..1655785 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| P5W76_RS07860 | - | 1655921..1656985 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| P5W76_RS07865 | cstB | 1657018..1658352 (+) | 1335 | Protein_1546 | persulfide dioxygenase-sulfurtransferase CstB | - |
| P5W76_RS07870 | - | 1658466..1659575 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| P5W76_RS07875 | psm-mec | 1659930..1659998 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| P5W76_RS07880 | mecI | 1660083..1660454 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| P5W76_RS07885 | mecR1 | 1660454..1662211 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| P5W76_RS07890 | mecA | 1662308..1664317 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=805675 P5W76_RS07815 WP_000816499.1 1649515..1650861(+) (ccrA) [Staphylococcus epidermidis strain 25DSE01]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=805675 P5W76_RS07815 WP_000816499.1 1649515..1650861(+) (ccrA) [Staphylococcus epidermidis strain 25DSE01]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |