Detailed information NTG0804331

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U66_RS09655
• Genome accession: NZ_CP120182
• Coordinates: 1950076..1951119 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Dog014
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1945076..1956119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U66_RS09625 (P3U66_09625)	-	1945498..1946754 (-)	1257	WP_001789555.1	aminopeptidase	-
P3U66_RS09630 (P3U66_09630)	-	1946757..1946957 (-)	201	WP_000180460.1	DUF1128 family protein	-
P3U66_RS09635 (P3U66_09635)	-	1947104..1947568 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P3U66_RS09640 (P3U66_09640)	-	1947575..1947850 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P3U66_RS09645 (P3U66_09645)	-	1948128..1949345 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
P3U66_RS09650 (P3U66_09650)	vraR	1949457..1950086 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P3U66_RS09655 (P3U66_09655)	vraS	1950076..1951119 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P3U66_RS09660 (P3U66_09660)	liaF	1951116..1951817 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P3U66_RS09665 (P3U66_09665)	-	1951832..1952218 (-)	387	WP_001110179.1	hypothetical protein	-
P3U66_RS09670 (P3U66_09670)	map	1952435..1953193 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
P3U66_RS09675 (P3U66_09675)	-	1953664..1954650 (+)	987	WP_043044165.1	FUSC family protein	-
P3U66_RS09680 (P3U66_09680)	-	1955082..1955495 (-)	414	WP_001566709.1	hypothetical protein	-
P3U66_RS09685 (P3U66_09685)	-	1955524..1955634 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=804331 P3U66_RS09655 WP_001017131.1 1950076..1951119(-) (vraS) [Staphylococcus aureus strain Dog014]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=804331 P3U66_RS09655 WP_001017131.1 1950076..1951119(-) (vraS) [Staphylococcus aureus strain Dog014]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1