Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RKV26_RS10700 Genome accession   NZ_CP134532
Coordinates   2126368..2127084 (+) Length   238 a.a.
NCBI ID   WP_209206015.1    Uniprot ID   -
Organism   Staphylococcus aureus strain KNIH_6268     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2121368..2132084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RKV26_RS10675 - 2122138..2123309 (+) 1172 Protein_2031 IS256-like element IS256 family transposase -
  RKV26_RS14395 hld 2123955..2124035 (-) 81 WP_000046022.1 delta-hemolysin -
  RKV26_RS10685 - 2124325..2124888 (+) 564 WP_115289668.1 accessory gene regulator AgrB -
  RKV26_RS10690 agrD 2124892..2125032 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  RKV26_RS10695 agrC 2125057..2126349 (+) 1293 WP_311163470.1 quorum-sensing sensor histidine kinase AgrC -
  RKV26_RS10700 agrA 2126368..2127084 (+) 717 WP_209206015.1 quorum-sensing response regulator AgrA Regulator
  RKV26_RS10705 - 2127156..2127263 (+) 108 WP_154284415.1 hypothetical protein -
  RKV26_RS10710 - 2127452..2128411 (-) 960 WP_154284416.1 carbohydrate kinase -
  RKV26_RS10715 - 2128408..2129892 (-) 1485 WP_154284417.1 sucrose-6-phosphate hydrolase -
  RKV26_RS10720 - 2130041..2130991 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27931.98 Da        Isoelectric Point: 6.0927

>NTDB_id=804307 RKV26_RS10700 WP_209206015.1 2126368..2127084(+) (agrA) [Staphylococcus aureus strain KNIH_6268]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDLKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=804307 RKV26_RS10700 WP_209206015.1 2126368..2127084(+) (agrA) [Staphylococcus aureus strain KNIH_6268]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCTCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTTGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996