Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   P3U05_RS03785 Genome accession   NZ_CP120179
Coordinates   852825..853541 (-) Length   238 a.a.
NCBI ID   WP_014613411.1    Uniprot ID   X2JA42
Organism   Staphylococcus pseudintermedius strain Dog018     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 847825..858541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3U05_RS03770 (P3U05_03770) - 849330..850277 (+) 948 WP_063278589.1 LacI family DNA-binding transcriptional regulator -
  P3U05_RS03775 (P3U05_03775) - 850333..851817 (+) 1485 WP_063278588.1 sucrose-6-phosphate hydrolase -
  P3U05_RS03780 (P3U05_03780) - 851821..852765 (+) 945 WP_311744869.1 carbohydrate kinase -
  P3U05_RS03785 (P3U05_03785) agrA 852825..853541 (-) 717 WP_014613411.1 quorum-sensing response regulator AgrA Regulator
  P3U05_RS03790 (P3U05_03790) agrC 853555..854847 (-) 1293 WP_096636795.1 quorum-sensing sensor histidine kinase AgrC -
  P3U05_RS03795 (P3U05_03795) agrD 854870..855007 (-) 138 WP_019166405.1 cyclic lactone autoinducer peptide AgrD -
  P3U05_RS03800 (P3U05_03800) - 855009..855575 (-) 567 WP_130921879.1 accessory gene regulator AgrB -
  P3U05_RS12230 - 855967..856044 (+) 78 WP_126511050.1 delta-lysin family phenol-soluble modulin -
  P3U05_RS03805 (P3U05_03805) - 856332..857135 (-) 804 WP_311744868.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28002.15 Da        Isoelectric Point: 5.4331

>NTDB_id=804207 P3U05_RS03785 WP_014613411.1 852825..853541(-) (agrA) [Staphylococcus pseudintermedius strain Dog018]
MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=804207 P3U05_RS03785 WP_014613411.1 852825..853541(-) (agrA) [Staphylococcus pseudintermedius strain Dog018]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGTATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGAAAATTGAGCTTGCTACCAATGACCCTTATGCTATCTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACGTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGGACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTAT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGTGGAACAAGCTCGGTTTACGTGAACTATGACGACGTGATG
TTTTTCGAGTCCTCACCGAAGTCACATCGTTTAATCGCACATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGATCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X2JA42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.193

100

0.832