Detailed information NTG0803755

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RJW56_RS10510
• Genome accession: NZ_CP134472
• Coordinates: 2128662..2131202 (-)
• Length: 846 a.a.
• NCBI ID: WP_043032946.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1522228
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2123662..2136202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW56_RS10485 (RJW56_10485)	-	2124820..2125563 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
RJW56_RS10490 (RJW56_10490)	-	2125563..2126366 (-)	804	WP_014637221.1	amino acid ABC transporter permease	-
RJW56_RS10495 (RJW56_10495)	-	2126552..2127403 (-)	852	WP_172015555.1	amino acid ABC transporter substrate-binding protein	-
RJW56_RS10500 (RJW56_10500)	-	2127436..2128122 (-)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
RJW56_RS10505 (RJW56_10505)	-	2128236..2128409 (-)	174	WP_009910995.1	hypothetical protein	-
RJW56_RS10510 (RJW56_10510)	hexA	2128662..2131202 (-)	2541	WP_043032946.1	DNA mismatch repair protein MutS	Machinery gene
RJW56_RS10515 (RJW56_10515)	argR	2131217..2131657 (-)	441	WP_002937036.1	arginine repressor	-
RJW56_RS10520 (RJW56_10520)	argS	2131764..2133452 (+)	1689	WP_009910998.1	arginine--tRNA ligase	-
RJW56_RS10525 (RJW56_10525)	-	2133632..2134546 (+)	915	WP_009911000.1	SH3 domain-containing protein	-
RJW56_RS10530 (RJW56_10530)	-	2134600..2135124 (-)	525	WP_024394551.1	membrane protein	-
RJW56_RS10535 (RJW56_10535)	-	2135236..2135418 (+)	183	WP_015647552.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95084.65 Da
• Isoelectric Point: 4.8195

>NTDB_id=803755 RJW56_RS10510 WP_043032946.1 2128662..2131202(-) (hexA) [Streptococcus suis strain 1522228]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVALDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNVPAIKNILLQMDQPALTSLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELTKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTTPAPIVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=803755 RJW56_RS10510 WP_043032946.1 2128662..2131202(-) (hexA) [Streptococcus suis strain 1522228]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCATGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGCTTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATTGGCTATGCTCTGTCAGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTTCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCGACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTTGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCTAGCCGGGTATCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCTCAGACCCTTGGAAATGTCCCTGCTATCAAGAATATCTTGCTACAAATGGACC
AGCCTGCTCTGACTAGCTTGGTGGCAGGTCTGGATCCAATCCCAGAACTACACGCCCTGATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTTAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATTTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGTTATGGAACGGAAGAGTTGACTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACTCGTATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCACTCATCCTCTTTGATGAGTTGGGGCGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACTCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGACAGGATTTTGCAGACGCTTGAAAACCAAGCTCCTACTGCACCAACTACCCCAGCTCCGATAGTCGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGCAAAACTGGATAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.232	100	0.742
mutS	Pseudomonas stutzeri strain ATCC 17587	37.631	100	0.383