Detailed information NTG0080305

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: L6478_RS20675
• Genome accession: NZ_AP022970
• Coordinates: 4000564..4001358 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus cereus strain J75
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3995564..4006358

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6478_RS20655 (BCJMU75_4082)	-	3997378..3997611 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
L6478_RS20660 (BCJMU75_4083)	-	3997660..3998388 (-)	729	WP_000172591.1	glycerophosphodiester phosphodiesterase	-
L6478_RS20665 (BCJMU75_4084)	-	3998439..3998582 (+)	144	WP_001247675.1	YycC family protein	-
L6478_RS20670 (BCJMU75_4085)	-	3998751..4000277 (-)	1527	WP_236787088.1	glycosyltransferase family 39 protein	-
L6478_RS20675 (BCJMU75_4086)	spo0A	4000564..4001358 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
L6478_RS20680 (BCJMU75_4087)	spoIVB	4001646..4002944 (-)	1299	WP_002054681.1	SpoIVB peptidase	-
L6478_RS20685 (BCJMU75_4088)	recN	4003063..4004802 (-)	1740	WP_062923516.1	DNA repair protein RecN	Machinery gene
L6478_RS20690 (BCJMU75_4089)	argR	4005070..4005519 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=80305 L6478_RS20675 WP_003161566.1 4000564..4001358(-) (spo0A) [Bacillus cereus strain J75]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=80305 L6478_RS20675 WP_003161566.1 4000564..4001358(-) (spo0A) [Bacillus cereus strain J75]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAGAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCGAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAACTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGACATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCTGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818