Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RI578_RS37740 Genome accession   NZ_CP134203
Coordinates   8221636..8222298 (+) Length   220 a.a.
NCBI ID   WP_310875298.1    Uniprot ID   -
Organism   Streptomyces sp. BB1-1-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8216636..8227298
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RI578_RS37725 (RI578_37725) - 8218272..8219576 (-) 1305 WP_310875295.1 ATP-grasp domain-containing protein -
  RI578_RS37730 (RI578_37730) - 8219909..8220283 (-) 375 WP_310875296.1 DUF6223 family protein -
  RI578_RS37735 (RI578_37735) - 8220512..8221639 (+) 1128 WP_310875297.1 sensor histidine kinase -
  RI578_RS37740 (RI578_37740) vraR 8221636..8222298 (+) 663 WP_310875298.1 response regulator transcription factor Regulator
  RI578_RS37745 (RI578_37745) - 8222331..8222876 (-) 546 WP_310875299.1 GNAT family N-acetyltransferase -
  RI578_RS37750 (RI578_37750) - 8223061..8223528 (+) 468 WP_310875300.1 MarR family winged helix-turn-helix transcriptional regulator -
  RI578_RS37755 (RI578_37755) - 8223581..8224582 (-) 1002 WP_310875301.1 ester cyclase -
  RI578_RS37760 (RI578_37760) - 8224655..8226001 (-) 1347 WP_310875302.1 MFS transporter -
  RI578_RS37765 (RI578_37765) - 8226126..8226893 (-) 768 WP_310875303.1 aldolase/citrate lyase family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23711.45 Da        Isoelectric Point: 5.1189

>NTDB_id=802724 RI578_RS37740 WP_310875298.1 8221636..8222298(+) (vraR) [Streptomyces sp. BB1-1-1]
MIRVLLVDDQPLIRSGFRALLALEDDIEVVAEAADGQEGLALVEKQLPDVVLIDIQMPVMDGIEATRRIAANPALAGVHV
VMLTNYGMDEYVFDALRAGAAGFLVKDIVPEDFLHAVRVAARGDALLAPAITRKLIDRYVTQPPPARARGGLEELTSRER
EAVALAAQGLSNDEIAARLVISPATAKTHINRAMAKLHARDRAQLVVLAYESGLVTPRNA

Nucleotide


Download         Length: 663 bp        

>NTDB_id=802724 RI578_RS37740 WP_310875298.1 8221636..8222298(+) (vraR) [Streptomyces sp. BB1-1-1]
GTGATCCGTGTCCTGCTGGTCGACGACCAGCCGCTCATCCGCAGCGGCTTCCGCGCGCTCCTCGCCCTCGAAGACGACAT
CGAGGTGGTGGCCGAGGCAGCCGACGGCCAAGAGGGCCTGGCGCTGGTCGAGAAGCAGCTGCCCGACGTCGTACTCATCG
ACATCCAGATGCCCGTCATGGACGGCATCGAAGCGACCCGGCGCATCGCCGCGAACCCGGCCCTGGCCGGGGTGCACGTC
GTCATGCTGACCAACTACGGCATGGACGAGTACGTCTTCGACGCGCTGCGCGCCGGCGCCGCCGGCTTCCTCGTCAAGGA
CATCGTGCCGGAGGACTTCCTGCACGCCGTACGCGTCGCCGCCCGCGGTGACGCCCTGCTCGCGCCCGCCATCACCCGCA
AGCTCATCGACCGGTACGTTACCCAGCCGCCCCCCGCCCGCGCCCGCGGCGGCCTGGAGGAACTGACCAGCCGCGAGCGT
GAGGCGGTCGCCCTCGCCGCACAGGGCCTGTCCAACGACGAGATCGCCGCCCGCCTGGTCATCAGCCCGGCGACCGCCAA
GACCCACATCAACCGGGCCATGGCCAAACTCCACGCCCGCGACCGCGCCCAGCTCGTGGTCCTCGCCTACGAATCAGGCC
TGGTCACCCCGCGCAACGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.674

97.727

0.368