Detailed information NTG0802710

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U69_RS04890
• Genome accession: NZ_CP120083
• Coordinates: 998804..999850 (+)
• Length: 348 a.a.
• NCBI ID: WP_011275375.1
• Uniprot ID: A0A2A1K920
• Organism: Staphylococcus haemolyticus strain Dog117_H
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 993804..1004850

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U69_RS04865 (P3U69_04865)	map	994664..995416 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
P3U69_RS04870 (P3U69_04870)	-	995541..996398 (-)	858	WP_323704920.1	SDR family oxidoreductase	-
P3U69_RS04875 (P3U69_04875)	-	996470..997482 (-)	1013	Protein_956	HoxN/HupN/NixA family nickel/cobalt transporter	-
P3U69_RS04880 (P3U69_04880)	-	997695..998081 (+)	387	WP_011275373.1	hypothetical protein	-
P3U69_RS04885 (P3U69_04885)	liaF	998106..998807 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
P3U69_RS04890 (P3U69_04890)	vraS	998804..999850 (+)	1047	WP_011275375.1	sensor histidine kinase	Regulator
P3U69_RS04895 (P3U69_04895)	vraR	999840..1000469 (+)	630	WP_011275376.1	two-component system response regulator VraR	Regulator
P3U69_RS04900 (P3U69_04900)	-	1000533..1001744 (-)	1212	WP_011275377.1	YihY/virulence factor BrkB family protein	-
P3U69_RS04905 (P3U69_04905)	-	1001941..1002225 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
P3U69_RS04910 (P3U69_04910)	-	1002231..1002695 (-)	465	WP_011275379.1	low molecular weight protein-tyrosine-phosphatase	-
P3U69_RS04915 (P3U69_04915)	-	1002837..1003046 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
P3U69_RS04920 (P3U69_04920)	-	1003060..1004307 (+)	1248	WP_011275381.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40179.58 Da
• Isoelectric Point: 6.0550

>NTDB_id=802710 P3U69_RS04890 WP_011275375.1 998804..999850(+) (vraS) [Staphylococcus haemolyticus strain Dog117_H]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIENERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=802710 P3U69_RS04890 WP_011275375.1 998804..999850(+) (vraS) [Staphylococcus haemolyticus strain Dog117_H]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATTGAGCATGCCATTGAAGGAGAAACAGTAGGTATCAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATCT
TTATCAAACATTAGTTCCTCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGAATGAACGACAGAGATTAGCTCGCGAGTTACATGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCTATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAATCTCAACTTGAAATGCGCGCATTATTACTTCATTTGAGACCTTTAGGACTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTTCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAGG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCATTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2A1K920

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914