Detailed information NTG0802565

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U38_RS04140
• Genome accession: NZ_CP120077
• Coordinates: 931493..932536 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain Dog121
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 926493..937536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U38_RS04115 (P3U38_04115)	-	926749..927471 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
P3U38_RS04120 (P3U38_04120)	-	928439..929437 (-)	999	WP_037542644.1	FUSC family protein	-
P3U38_RS04125 (P3U38_04125)	map	929534..930295 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
P3U38_RS04130 (P3U38_04130)	-	930393..930782 (+)	390	WP_014613479.1	hypothetical protein	-
P3U38_RS04135 (P3U38_04135)	liaF	930795..931496 (+)	702	WP_110168740.1	cell wall-active antibiotics response protein LiaF	-
P3U38_RS04140 (P3U38_04140)	vraS	931493..932536 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
P3U38_RS04145 (P3U38_04145)	vraR	932526..933155 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
P3U38_RS04150 (P3U38_04150)	-	933722..934303 (-)	582	WP_063278570.1	beta-class carbonic anhydrase	-
P3U38_RS04155 (P3U38_04155)	-	934336..935673 (-)	1338	WP_015729387.1	YihY/virulence factor BrkB family protein	-
P3U38_RS04160 (P3U38_04160)	-	935889..936176 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
P3U38_RS04165 (P3U38_04165)	-	936184..936642 (-)	459	WP_140239540.1	low molecular weight protein-tyrosine-phosphatase	-
P3U38_RS04170 (P3U38_04170)	-	936776..936979 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=802565 P3U38_RS04140 WP_014613481.1 931493..932536(+) (vraS) [Staphylococcus pseudintermedius strain Dog121]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=802565 P3U38_RS04140 WP_014613481.1 931493..932536(+) (vraS) [Staphylococcus pseudintermedius strain Dog121]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839