Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q2K21_RS09445 Genome accession   NZ_CP134053
Coordinates   2254785..2255462 (+) Length   225 a.a.
NCBI ID   WP_310768728.1    Uniprot ID   A0ABV7SD96
Organism   Streptomyces sp. CGMCC 4.7035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2249785..2260462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2K21_RS09425 (Q2K21_09425) - 2249797..2250027 (-) 231 WP_109495566.1 hypothetical protein -
  Q2K21_RS09430 (Q2K21_09430) - 2250469..2252592 (+) 2124 WP_310768722.1 DNA topoisomerase IV subunit B -
  Q2K21_RS09435 (Q2K21_09435) - 2253116..2253640 (+) 525 WP_310768724.1 DUF1453 domain-containing protein -
  Q2K21_RS09440 (Q2K21_09440) - 2253637..2254788 (+) 1152 WP_310768726.1 histidine kinase -
  Q2K21_RS09445 (Q2K21_09445) vraR 2254785..2255462 (+) 678 WP_310768728.1 response regulator transcription factor Regulator
  Q2K21_RS09450 (Q2K21_09450) - 2255532..2256098 (+) 567 WP_310768730.1 DUF485 domain-containing protein -
  Q2K21_RS09455 (Q2K21_09455) - 2256095..2257687 (+) 1593 WP_310768732.1 cation acetate symporter -
  Q2K21_RS09460 (Q2K21_09460) - 2257785..2258477 (-) 693 WP_310768734.1 response regulator -
  Q2K21_RS09465 (Q2K21_09465) - 2258638..2259453 (+) 816 WP_310768737.1 ABC transporter ATP-binding protein -
  Q2K21_RS09470 (Q2K21_09470) - 2259443..2260306 (+) 864 WP_310768740.1 ABC transporter permease -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23973.35 Da        Isoelectric Point: 5.1580

>NTDB_id=802001 Q2K21_RS09445 WP_310768728.1 2254785..2255462(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
MTEEGSRKAARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGDEAVKLVAELAPDVVLMDLRMPRCDGVEATRRIRAE
HPGTQVVVLTTYADDESLFPALRAGARGYLTKDAGGDEIVRAVHSVLSGDAGLSPSIQRRLLERLSDPEPPAAAEAPDGL
TAREKEVLVLIAEGLTNQEIARRLHVSTATVKTHINNLFAKTGLKDRAQAVRYAYANGLVQPPSQ

Nucleotide


Download         Length: 678 bp        

>NTDB_id=802001 Q2K21_RS09445 WP_310768728.1 2254785..2255462(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
ATGACGGAGGAGGGGAGCAGGAAGGCCGCCCGGGTTGTGGTGGCGGACGATCAGACGGTGGTGCGGGAGGGCATCGTGAT
GCTGCTCGGGCTACTTCCAGGAATCGAGGTCGTCGGTGCCGCCGGCGACGGGGACGAGGCTGTGAAGCTCGTCGCCGAAC
TCGCCCCGGACGTGGTGCTGATGGACCTGCGCATGCCGCGTTGCGACGGCGTCGAGGCGACCCGGCGTATCCGCGCCGAG
CACCCCGGCACCCAGGTCGTCGTGCTCACCACCTATGCGGACGACGAGTCGCTGTTCCCGGCGCTGAGAGCAGGAGCGCG
CGGCTATCTCACCAAGGACGCGGGCGGGGACGAGATCGTGCGGGCCGTGCACAGCGTGCTGTCCGGAGACGCCGGGCTCT
CGCCGAGCATTCAACGACGGTTGCTGGAGCGGCTGTCGGACCCGGAGCCGCCCGCGGCCGCGGAGGCGCCGGACGGACTC
ACCGCACGGGAGAAGGAGGTGCTCGTACTGATCGCCGAGGGGCTGACCAACCAGGAGATCGCCCGCAGACTGCATGTCTC
CACGGCCACCGTGAAGACCCACATCAACAATCTCTTCGCCAAGACGGGGCTCAAAGACCGTGCTCAGGCGGTCCGTTACG
CGTATGCCAACGGGCTGGTGCAGCCACCTTCGCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-214)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.336

93.778

0.369