Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   RE424_RS09205 Genome accession   NZ_CP134047
Coordinates   1862874..1864148 (+) Length   424 a.a.
NCBI ID   WP_001279338.1    Uniprot ID   A0A0H2XGV4
Organism   Staphylococcus aureus strain 21SAU_AGRO3     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1857874..1869148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RE424_RS09185 - 1859198..1859293 (+) 96 WP_031761395.1 hypothetical protein -
  RE424_RS09190 - 1859254..1860384 (-) 1131 WP_023914769.1 HAD family hydrolase -
  RE424_RS09195 nagE 1860491..1861957 (-) 1467 WP_103254253.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  RE424_RS09200 - 1862085..1862702 (-) 618 WP_000287588.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  RE424_RS09205 htrA 1862874..1864148 (+) 1275 WP_001279338.1 S1C family serine protease Regulator
  RE424_RS09210 tyrS 1864242..1865504 (-) 1263 WP_000186029.1 tyrosine--tRNA ligase -
  RE424_RS09215 - 1865885..1866790 (+) 906 WP_000184370.1 transglycosylase domain-containing protein -
  RE424_RS09220 - 1866770..1866862 (-) 93 WP_031761401.1 hypothetical protein -

Sequence

Protein


Download         Length: 424 a.a.        Molecular weight: 45802.98 Da        Isoelectric Point: 9.9696

>NTDB_id=801945 RE424_RS09205 WP_001279338.1 1862874..1864148(+) (htrA) [Staphylococcus aureus strain 21SAU_AGRO3]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide


Download         Length: 1275 bp        

>NTDB_id=801945 RE424_RS09205 WP_001279338.1 1862874..1864148(+) (htrA) [Staphylococcus aureus strain 21SAU_AGRO3]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACTATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGTGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-269)

PDZ domain (PDZ_2)

(307-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

39.055

94.811

0.37