Detailed information NTG0801869

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U39_RS03990
• Genome accession: NZ_CP120027
• Coordinates: 899794..900837 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain Dog143
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 894794..905837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U39_RS03965 (P3U39_03965)	-	895050..895772 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
P3U39_RS03970 (P3U39_03970)	-	896740..897738 (-)	999	WP_014613477.1	FUSC family protein	-
P3U39_RS03975 (P3U39_03975)	map	897835..898596 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
P3U39_RS03980 (P3U39_03980)	-	898694..899083 (+)	390	WP_014613479.1	hypothetical protein	-
P3U39_RS03985 (P3U39_03985)	liaF	899096..899797 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
P3U39_RS03990 (P3U39_03990)	vraS	899794..900837 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
P3U39_RS03995 (P3U39_03995)	vraR	900827..901456 (+)	630	WP_070407820.1	response regulator transcription factor	Regulator
P3U39_RS04000 (P3U39_04000)	-	902023..902604 (-)	582	WP_015729388.1	beta-class carbonic anhydrase	-
P3U39_RS04005 (P3U39_04005)	-	902637..903974 (-)	1338	WP_014613484.1	YihY/virulence factor BrkB family protein	-
P3U39_RS04010 (P3U39_04010)	-	904190..904477 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
P3U39_RS04015 (P3U39_04015)	-	904485..904943 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
P3U39_RS04020 (P3U39_04020)	-	905077..905280 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=801869 P3U39_RS03990 WP_014613481.1 899794..900837(+) (vraS) [Staphylococcus pseudintermedius strain Dog143]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=801869 P3U39_RS03990 WP_014613481.1 899794..900837(+) (vraS) [Staphylococcus pseudintermedius strain Dog143]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839