Detailed information NTG0801643

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U67_RS09555
• Genome accession: NZ_CP120011
• Coordinates: 1942279..1943322 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Dog156
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1937279..1948322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U67_RS09525 (P3U67_09525)	-	1937701..1938957 (-)	1257	WP_072419726.1	aminopeptidase	-
P3U67_RS09530 (P3U67_09530)	-	1938960..1939160 (-)	201	WP_000180460.1	DUF1128 family protein	-
P3U67_RS09535 (P3U67_09535)	-	1939307..1939771 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P3U67_RS09540 (P3U67_09540)	-	1939778..1940053 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P3U67_RS09545 (P3U67_09545)	-	1940331..1941548 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
P3U67_RS09550 (P3U67_09550)	vraR	1941660..1942289 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
P3U67_RS09555 (P3U67_09555)	vraS	1942279..1943322 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P3U67_RS09560 (P3U67_09560)	liaF	1943319..1944020 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P3U67_RS09565 (P3U67_09565)	-	1944035..1944421 (-)	387	WP_001110179.1	hypothetical protein	-
P3U67_RS09570 (P3U67_09570)	map	1944638..1945396 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
P3U67_RS09575 (P3U67_09575)	-	1945812..1946798 (+)	987	WP_000999713.1	FUSC family protein	-
P3U67_RS09580 (P3U67_09580)	-	1947288..1947701 (-)	414	WP_001566709.1	hypothetical protein	-
P3U67_RS09585 (P3U67_09585)	-	1947730..1947840 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=801643 P3U67_RS09555 WP_001017131.1 1942279..1943322(-) (vraS) [Staphylococcus aureus strain Dog156]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=801643 P3U67_RS09555 WP_001017131.1 1942279..1943322(-) (vraS) [Staphylococcus aureus strain Dog156]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1