Detailed information NTG0801421

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3T93_RS04680
• Genome accession: NZ_CP119997
• Coordinates: 957708..958751 (+)
• Length: 347 a.a.
• NCBI ID: WP_019469615.1
• Uniprot ID: A0A6N7XY82
• Organism: Staphylococcus cohnii strain Dog166
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 952708..963751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3T93_RS04655 (P3T93_04655)	-	953776..954498 (+)	723	WP_064264271.1	type 1 glutamine amidotransferase	-
P3T93_RS04660 (P3T93_04660)	-	954587..955573 (-)	987	WP_064264273.1	aromatic acid exporter family protein	-
P3T93_RS04665 (P3T93_04665)	map	955750..956502 (+)	753	WP_064264275.1	type I methionyl aminopeptidase	-
P3T93_RS04670 (P3T93_04670)	-	956607..956993 (+)	387	WP_019469613.1	hypothetical protein	-
P3T93_RS04675 (P3T93_04675)	liaF	957010..957711 (+)	702	WP_019469614.1	cell wall-active antibiotics response protein LiaF	-
P3T93_RS04680 (P3T93_04680)	vraS	957708..958751 (+)	1044	WP_019469615.1	sensor histidine kinase	Regulator
P3T93_RS04685 (P3T93_04685)	vraR	958741..959370 (+)	630	WP_019469616.1	response regulator transcription factor	Regulator
P3T93_RS04690 (P3T93_04690)	-	959458..960537 (-)	1080	WP_064264279.1	YihY/virulence factor BrkB family protein	-
P3T93_RS04695 (P3T93_04695)	-	960850..961134 (-)	285	WP_019469618.1	YtxH domain-containing protein	-
P3T93_RS04700 (P3T93_04700)	-	961142..961606 (-)	465	WP_064264281.1	low molecular weight protein-tyrosine-phosphatase	-
P3T93_RS04705 (P3T93_04705)	-	961739..961942 (+)	204	WP_064264282.1	DUF1128 family protein	-
P3T93_RS04710 (P3T93_04710)	-	961957..963195 (+)	1239	WP_150889860.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40030.41 Da
• Isoelectric Point: 5.8532

>NTDB_id=801421 P3T93_RS04680 WP_019469615.1 957708..958751(+) (vraS) [Staphylococcus cohnii strain Dog166]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHRLRLKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EEFDVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=801421 P3T93_RS04680 WP_019469615.1 957708..958751(+) (vraS) [Staphylococcus cohnii strain Dog166]
ATGAATCACTACATAAGAGCAATAGGGTCAATGTTGATATTAGTTTATAGTACATTTTTCGCTATGTTTTTTATAGATAA
AGTTTTTGTGAATATTATATATTTTCAAGGCATGATTTATACGCAAATCTTTGGAATACCAGTTTTACTATTTATTAACT
TATTAGTTATATTACTTTGCATCATTGTTGGCTCAGTATTAGCTTATAAAATCAATCAACAAAATCATTGGTTACAAGAC
CAAATTGAGCGTTCTATAGAAGGGCAGACAGTAGGTATCAATGACCAAAATATAGAATTATATAATGAAACAATTGAATT
ATATCAAACGCTTGTACCGCTCAATCAAGAAGTTCATAGATTGCGTTTAAAAACACAAAATTTAACGAATGAATCATATA
ATATGAACGATGTGAAAGTTAAAAAAATAATTGAAGATGAAAGACAAAGACTGGCTCGAGAGTTACATGATTCCGTAAGC
CAGCAATTGTTTGCAGCAAGCATGATGCTCTCTGCCATTAAAGAAACTGATTTGAAAGCGCCTTTAGATCAACAAATTCC
AGTATTGGAAAAAATGATTCAAGATTCACAGCTAGAAATGCGTGCCTTGCTATTACATTTAAGACCAATTGGCTTGAAAG
ATAAATCACTTGGCCAAGGTATCAAAGATTTAGTGGTTGATTTGCAGAAAAAAGTGCCTATGAAAGTTGTACATGATATT
GAAGAATTCGACGTACCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAAGCAATTTCAAATACATTAAGACA
TTCAAAAGGGACAAAAGTTACAATTGAATTGTTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGATGGTAAAG
GCTTTAACGTAGATGATAAGGTAGAACAAAGCTATGGGTTAAAAAATATGCGCGAACGAGCACTTGAAATTGGCGCAACG
TTTCATATAGTATCACTGCCAGATTCAGGAACACGAATTGAAGTCAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A6N7XY82

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.455	100	0.865