Detailed information NTG0800804

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: P3K50_RS13395
• Genome accession: NZ_CP119715
• Coordinates: 2702321..2703208 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CUVET17-649
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2697321..2708208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3K50_RS13365 (P3K50_13335)	-	2697330..2697422 (+)	93	WP_031774855.1	hypothetical protein	-
P3K50_RS13370 (P3K50_13340)	-	2697530..2698027 (-)	498	WP_001065267.1	glutathione peroxidase	-
P3K50_RS13375 (P3K50_13345)	-	2698037..2698297 (-)	261	WP_014937088.1	hypothetical protein	-
P3K50_RS13380 (P3K50_13350)	-	2698679..2698792 (-)	114	WP_014937089.1	hypothetical protein	-
P3K50_RS13385 (P3K50_13355)	-	2699461..2701461 (-)	2001	WP_000776741.1	ABC transporter permease	-
P3K50_RS13390 (P3K50_13360)	-	2701458..2702213 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
P3K50_RS13395 (P3K50_13365)	braS	2702321..2703208 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
P3K50_RS13400 (P3K50_13370)	braR	2703219..2703884 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
P3K50_RS13405 (P3K50_13375)	-	2703910..2704110 (-)	201	WP_000604731.1	hypothetical protein	-
P3K50_RS13410 (P3K50_13380)	-	2704308..2705732 (+)	1425	WP_000953736.1	alkaline phosphatase	-
P3K50_RS13415	-	2705792..2705893 (-)	102	WP_000731972.1	SE2200 family small protein	-
P3K50_RS13420 (P3K50_13390)	-	2706015..2706470 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
P3K50_RS13425 (P3K50_13395)	-	2706714..2707475 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=800804 P3K50_RS13395 WP_000143420.1 2702321..2703208(-) (braS) [Staphylococcus aureus strain CUVET17-649]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=800804 P3K50_RS13395 WP_000143420.1 2702321..2703208(-) (braS) [Staphylococcus aureus strain CUVET17-649]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993