Detailed information NTG0800761

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: P3K41_RS13450
• Genome accession: NZ_CP119713
• Coordinates: 2714582..2715469 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CUVET17-948
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2709582..2720469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3K41_RS13420 (P3K41_13380)	-	2709591..2709683 (+)	93	WP_031774855.1	hypothetical protein	-
P3K41_RS13425 (P3K41_13385)	-	2709791..2710288 (-)	498	WP_001065267.1	glutathione peroxidase	-
P3K41_RS13430 (P3K41_13390)	-	2710298..2710558 (-)	261	WP_014937088.1	hypothetical protein	-
P3K41_RS13435 (P3K41_13395)	-	2710940..2711053 (-)	114	WP_014937089.1	hypothetical protein	-
P3K41_RS13440 (P3K41_13400)	-	2711722..2713722 (-)	2001	WP_000776741.1	ABC transporter permease	-
P3K41_RS13445 (P3K41_13405)	-	2713719..2714474 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
P3K41_RS13450 (P3K41_13410)	braS	2714582..2715469 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
P3K41_RS13455 (P3K41_13415)	braR	2715480..2716145 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
P3K41_RS13460 (P3K41_13420)	-	2716171..2716371 (-)	201	WP_000604731.1	hypothetical protein	-
P3K41_RS13465 (P3K41_13425)	-	2716569..2717993 (+)	1425	WP_000953736.1	alkaline phosphatase	-
P3K41_RS13470	-	2718053..2718154 (-)	102	WP_000731972.1	SE2200 family small protein	-
P3K41_RS13475 (P3K41_13435)	-	2718276..2718731 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
P3K41_RS13480 (P3K41_13440)	-	2718975..2719736 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=800761 P3K41_RS13450 WP_000143420.1 2714582..2715469(-) (braS) [Staphylococcus aureus strain CUVET17-948]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=800761 P3K41_RS13450 WP_000143420.1 2714582..2715469(-) (braS) [Staphylococcus aureus strain CUVET17-948]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993