Detailed information NTG0800719

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: P3K49_RS13365
• Genome accession: NZ_CP119710
• Coordinates: 2698048..2698935 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CUVET17-1695
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2693048..2703935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3K49_RS13335 (P3K49_13300)	-	2693057..2693149 (+)	93	WP_031774855.1	hypothetical protein	-
P3K49_RS13340 (P3K49_13305)	-	2693257..2693754 (-)	498	WP_001065267.1	glutathione peroxidase	-
P3K49_RS13345 (P3K49_13310)	-	2693764..2694024 (-)	261	WP_014937088.1	hypothetical protein	-
P3K49_RS13350 (P3K49_13315)	-	2694406..2694519 (-)	114	WP_014937089.1	hypothetical protein	-
P3K49_RS13355 (P3K49_13320)	-	2695188..2697188 (-)	2001	WP_000776741.1	ABC transporter permease	-
P3K49_RS13360 (P3K49_13325)	-	2697185..2697940 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
P3K49_RS13365 (P3K49_13330)	braS	2698048..2698935 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
P3K49_RS13370 (P3K49_13335)	braR	2698946..2699611 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
P3K49_RS13375 (P3K49_13340)	-	2699637..2699837 (-)	201	WP_000604731.1	hypothetical protein	-
P3K49_RS13380 (P3K49_13345)	-	2700035..2701459 (+)	1425	WP_000953736.1	alkaline phosphatase	-
P3K49_RS13385	-	2701519..2701620 (-)	102	WP_000731972.1	SE2200 family small protein	-
P3K49_RS13390 (P3K49_13355)	-	2701742..2702197 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
P3K49_RS13395 (P3K49_13360)	-	2702441..2703202 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=800719 P3K49_RS13365 WP_000143420.1 2698048..2698935(-) (braS) [Staphylococcus aureus strain CUVET17-1695]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=800719 P3K49_RS13365 WP_000143420.1 2698048..2698935(-) (braS) [Staphylococcus aureus strain CUVET17-1695]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993