Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   P3K49_RS10025 Genome accession   NZ_CP119710
Coordinates   2045885..2046601 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CUVET17-1695     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2040885..2051601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3K49_RS09995 (P3K49_09975) - 2041152..2041778 (+) 627 WP_000522384.1 nitroreductase family protein -
  P3K49_RS10000 (P3K49_09980) - 2042086..2042871 (+) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  P3K49_RS10005 hld 2043473..2043553 (-) 81 WP_000046022.1 delta-hemolysin -
  P3K49_RS10010 (P3K49_09990) agrB 2043843..2044412 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  P3K49_RS10015 (P3K49_09995) agrD 2044409..2044549 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  P3K49_RS10020 (P3K49_10000) agrC 2044574..2045866 (+) 1293 WP_316794914.1 quorum-sensing sensor histidine kinase AgrC -
  P3K49_RS10025 (P3K49_10005) agrA 2045885..2046601 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  P3K49_RS10030 (P3K49_10010) - 2046975..2047934 (-) 960 WP_001253294.1 carbohydrate kinase -
  P3K49_RS10035 (P3K49_10015) - 2047931..2049415 (-) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  P3K49_RS10040 (P3K49_10020) - 2049564..2050514 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=800715 P3K49_RS10025 WP_000688492.1 2045885..2046601(+) (agrA) [Staphylococcus aureus strain CUVET17-1695]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=800715 P3K49_RS10025 WP_000688492.1 2045885..2046601(+) (agrA) [Staphylococcus aureus strain CUVET17-1695]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1