Detailed information NTG0800210

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: RFN65_RS20505
• Genome accession: NZ_CP133703
• Coordinates: 3977267..3978349 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain CP35
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3972267..3983349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RFN65_RS20480 (RFN65_20480)	cysE	3972372..3973025 (-)	654	WP_003225749.1	serine O-acetyltransferase	-
RFN65_RS20485 (RFN65_20485)	gltX	3973327..3974778 (-)	1452	WP_014478617.1	glutamate--tRNA ligase	-
RFN65_RS20490 (RFN65_20490)	ispF	3974869..3975345 (-)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
RFN65_RS20495 (RFN65_20495)	ispD	3975338..3976036 (-)	699	WP_015252991.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
RFN65_RS20500 (RFN65_20500)	yacL	3976051..3977151 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
RFN65_RS20505 (RFN65_20505)	disA	3977267..3978349 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
RFN65_RS20510 (RFN65_20510)	radA/sms	3978353..3979729 (-)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
RFN65_RS20515 (RFN65_20515)	clpC	3979821..3982253 (-)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
RFN65_RS20520 (RFN65_20520)	mcsB	3982250..3983341 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=800210 RFN65_RS20505 WP_003225736.1 3977267..3978349(-) (disA) [Bacillus subtilis strain CP35]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=800210 RFN65_RS20505 WP_003225736.1 3977267..3978349(-) (disA) [Bacillus subtilis strain CP35]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATCAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTGATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACGCTTGAAAAATATAAGACAATCCTCGACAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGACATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTACCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1