Detailed information NTG0799829

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P1289_RS11410
• Genome accession: NZ_CP119589
• Coordinates: 2439031..2440074 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain H-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2434031..2445074

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1289_RS11385 (P1289_11355)	-	2434985..2435707 (+)	723	WP_042362406.1	type 1 glutamine amidotransferase	-
P1289_RS11390 (P1289_11360)	-	2435910..2436896 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
P1289_RS11395 (P1289_11365)	map	2437073..2437825 (+)	753	WP_039069016.1	type I methionyl aminopeptidase	-
P1289_RS11400 (P1289_11370)	-	2437930..2438316 (+)	387	WP_042362408.1	hypothetical protein	-
P1289_RS11405 (P1289_11375)	liaF	2438333..2439034 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
P1289_RS11410 (P1289_11380)	vraS	2439031..2440074 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
P1289_RS11415 (P1289_11385)	vraR	2440064..2440693 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
P1289_RS11420 (P1289_11390)	-	2440962..2442107 (-)	1146	WP_042362411.1	YihY/virulence factor BrkB family protein	-
P1289_RS11425 (P1289_11395)	-	2442463..2442747 (-)	285	WP_042362412.1	hypothetical protein	-
P1289_RS11430 (P1289_11400)	-	2442754..2443218 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
P1289_RS11435 (P1289_11405)	-	2443353..2443556 (+)	204	WP_017723498.1	DUF1128 family protein	-
P1289_RS11440 (P1289_11410)	-	2443574..2444812 (+)	1239	WP_225523038.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=799829 P1289_RS11410 WP_042362410.1 2439031..2440074(+) (vraS) [Staphylococcus xylosus strain H-1]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=799829 P1289_RS11410 WP_042362410.1 2439031..2440074(+) (vraS) [Staphylococcus xylosus strain H-1]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCACTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885