Detailed information NTG0799754

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: P1I87_RS09215
• Genome accession: NZ_CP119576
• Coordinates: 1785076..1786149 (-)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain Guangzhou-SAG092
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1780076..1791149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1I87_RS09195 (P1I87_09195)	-	1781350..1781865 (-)	516	WP_000919802.1	VanZ family protein	-
P1I87_RS09200 (P1I87_09200)	rlmN	1781865..1782971 (-)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
P1I87_RS09205 (P1I87_09205)	-	1783022..1783600 (-)	579	WP_001224500.1	YutD-like domain-containing protein	-
P1I87_RS09210 (P1I87_09210)	-	1783669..1785001 (-)	1333	Protein_1743	metallophosphoesterase	-
P1I87_RS09215 (P1I87_09215)	sepM	1785076..1786149 (-)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
P1I87_RS09220 (P1I87_09220)	coaD	1786139..1786624 (-)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
P1I87_RS09225 (P1I87_09225)	-	1786621..1786911 (-)	291	WP_000384889.1	hypothetical protein	-
P1I87_RS09230 (P1I87_09230)	rsmD	1786923..1787462 (-)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
P1I87_RS09235 (P1I87_09235)	-	1787592..1788041 (+)	450	WP_000592263.1	thiol reductase thioredoxin	-
P1I87_RS09240 (P1I87_09240)	asnA	1788086..1789078 (-)	993	WP_000748011.1	aspartate--ammonia ligase	-
P1I87_RS09245 (P1I87_09245)	-	1789192..1790256 (-)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=799754 P1I87_RS09215 WP_000796095.1 1785076..1786149(-) (sepM) [Streptococcus agalactiae strain Guangzhou-SAG092]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=799754 P1I87_RS09215 WP_000796095.1 1785076..1786149(-) (sepM) [Streptococcus agalactiae strain Guangzhou-SAG092]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658