Detailed information NTG0799654

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: RDV59_RS01325
• Genome accession: NZ_CP133476
• Coordinates: 240684..243215 (+)
• Length: 843 a.a.
• NCBI ID: WP_371212499.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain LMG 11489
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 235684..248215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV59_RS01305 (RDV59_01305)	-	235877..237178 (+)	1302	WP_038675005.1	hypothetical protein	-
RDV59_RS01310 (RDV59_01310)	argS	238031..239722 (-)	1692	WP_038675007.1	arginine--tRNA ligase	-
RDV59_RS01315 (RDV59_01315)	argR	239877..240305 (+)	429	WP_171963651.1	arginine repressor	-
RDV59_RS01320 (RDV59_01320)	-	240305..240664 (+)	360	WP_038675011.1	YlbF family regulator	-
RDV59_RS01325 (RDV59_01325)	hexA	240684..243215 (+)	2532	WP_371212499.1	DNA mismatch repair protein MutS	Machinery gene
RDV59_RS01330 (RDV59_01330)	-	243249..243704 (-)	456	WP_002886315.1	DUF3021 domain-containing protein	-
RDV59_RS01335 (RDV59_01335)	-	243701..244138 (-)	438	WP_038675015.1	LytTR family DNA-binding domain-containing protein	-
RDV59_RS01340 (RDV59_01340)	-	244317..244619 (+)	303	WP_038675017.1	hypothetical protein	-
RDV59_RS01345 (RDV59_01345)	hexB	244672..246615 (+)	1944	WP_038675019.1	DNA mismatch repair endonuclease MutL	Machinery gene
RDV59_RS01350 (RDV59_01350)	-	246746..246967 (+)	222	WP_038675022.1	hypothetical protein	-
RDV59_RS01355 (RDV59_01355)	ruvA	247124..247714 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94635.63 Da
• Isoelectric Point: 4.6360

>NTDB_id=799654 RDV59_RS01325 WP_371212499.1 240684..243215(+) (hexA) [Streptococcus salivarius strain LMG 11489]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERYG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSHTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=799654 RDV59_RS01325 WP_371212499.1 240684..243215(+) (hexA) [Streptococcus salivarius strain LMG 11489]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTATCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAGATTTTGGTCAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACCAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAGAACGGGCAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGCACTTGGATTGATCGTCCTTTAGTGAATCAGG
CTGCAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGCTTAGCCAGTCGAGTTTCCTTTGGCAAGGCTAATCCTAAAGATTTGATTCAACTAGG
TCATACCTTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATGATGAGGCCTTGTCACGTCTTTTACAAG
AATTGGATGCTCTGCCAGAATTAGAAAGTCTGATTCGGTCAGCTATTGATCCCGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACGTCATGGATTGCGGA
TATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAATTCAGAGCGCTATGGA
ACCGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAGTCATCAACGCTCGAATATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCCATTGCGACAGTCGATGTTCTTC
AGAGCTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCATACCAA
TGTTCAGCTCATCACAGGGCCAAATATGAGTGGTAAATCTACCTATATGCGTCAGTTGGCTTTGTCAGTCGTTATGGCTC
AGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCTATCTATACACGTATTGGTGCTGCAGAT
GATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTAGGACGTGGGACAGCCACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTGGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTACGTGATTTGGACATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (590-776)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain I (MutS_I) (1-109)

• MutS domain III (MutS_III) (247-537)

• MutS domain II (MutS_II) (117-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.731	100	0.365