Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   P1T45_RS02265 Genome accession   NZ_CP119427
Coordinates   398542..399297 (+) Length   251 a.a.
NCBI ID   WP_003108564.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KSP45     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 393542..404297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1T45_RS02250 (P1T45_02250) - 393846..395414 (-) 1569 WP_037620382.1 ABC transporter substrate-binding protein/permease -
  P1T45_RS02255 (P1T45_02255) - 395620..397524 (+) 1905 WP_003108567.1 DUF2207 domain-containing protein -
  P1T45_RS02260 (P1T45_02260) - 397599..398438 (+) 840 WP_003108565.1 undecaprenyl-diphosphate phosphatase -
  P1T45_RS02265 (P1T45_02265) mecA 398542..399297 (+) 756 WP_003108564.1 adaptor protein MecA Regulator
  P1T45_RS02270 (P1T45_02270) - 399304..400461 (+) 1158 WP_003108563.1 glycosyltransferase family 4 protein -
  P1T45_RS02275 (P1T45_02275) sufC 400586..401356 (+) 771 WP_003108562.1 Fe-S cluster assembly ATPase SufC -
  P1T45_RS02280 (P1T45_02280) sufD 401445..402707 (+) 1263 WP_003102572.1 Fe-S cluster assembly protein SufD -
  P1T45_RS02285 (P1T45_02285) - 402732..403958 (+) 1227 WP_003108561.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29185.92 Da        Isoelectric Point: 4.1299

>NTDB_id=799235 P1T45_RS02265 WP_003108564.1 398542..399297(+) (mecA) [Streptococcus parauberis strain KSP45]
MEMKQISETTLKIMISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKDINFEDLAELGDISQMTPEDFFKTIEKNMMEKGDVDAHQKLEKIEEMLEDASAQAQEQAKVAEQEEYEAEVLDYVHFV
LSFASIEDAINFSKTIDFPIEASELYKESKSYHMTILLDVQNQPSYYANVSYARLIEHANPGIRTRAYLQEHGIQLIEDN
AVEELKKIEMV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=799235 P1T45_RS02265 WP_003108564.1 398542..399297(+) (mecA) [Streptococcus parauberis strain KSP45]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATAATGATCAGCATGGATGATTTAGAAGAAAGAGGTATGGAATT
AAAAGATTTCTTGATTCCACAAGAAAAGACCGAAGAATTTTTCTATTCAGTTATGGATGAACTTGATTTACCAGAAAACT
TTAAAGATAGTGGTATGCTTAGTTTCAGAGTGACACCTCGAAAAGACCGATTAGATGTCTTTGTTACAAAATCAGAATTA
AGTAAAGACATCAATTTTGAAGATTTAGCTGAACTAGGTGATATTTCACAAATGACGCCTGAAGATTTTTTCAAAACGAT
TGAAAAAAACATGATGGAAAAAGGTGATGTCGATGCTCACCAAAAATTAGAGAAAATTGAAGAAATGCTTGAGGATGCCT
CTGCTCAGGCGCAGGAGCAAGCAAAAGTTGCTGAACAAGAAGAGTATGAAGCAGAAGTTCTTGATTATGTTCACTTCGTA
TTGAGTTTTGCTTCTATTGAAGATGCAATTAATTTTTCAAAAACAATTGATTTCCCAATTGAAGCATCTGAGTTATATAA
GGAAAGCAAAAGTTATCACATGACTATTTTATTAGATGTTCAAAATCAACCTTCATATTATGCAAATGTTAGCTATGCAC
GTTTAATTGAACATGCTAATCCTGGGATTAGGACCAGAGCTTATTTACAAGAGCATGGCATTCAATTAATTGAAGATAAT
GCTGTTGAAGAATTGAAAAAAATTGAGATGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.71

98.805

0.629
  mecA Streptococcus thermophilus LMD-9

57.258

98.805

0.566
  mecA Streptococcus thermophilus LMG 18311

56.452

98.805

0.558
  mecA Streptococcus pneumoniae Rx1

47.431

100

0.478
  mecA Streptococcus pneumoniae D39

47.431

100

0.478
  mecA Streptococcus pneumoniae R6

47.431

100

0.478
  mecA Streptococcus pneumoniae TIGR4

47.431

100

0.478