Detailed information NTG0799004

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: P0M22_RS16750
• Genome accession: NZ_CP119399
• Coordinates: 3395272..3396435 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain HBXN2020
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3390272..3401435

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P0M22_RS16720 (P0M22_16720)	-	3390536..3390955 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
P0M22_RS16725 (P0M22_16725)	comFC	3391029..3391718 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
P0M22_RS16730 (P0M22_16730)	-	3391724..3392008 (-)	285	WP_003151389.1	competence protein ComFB	-
P0M22_RS16735 (P0M22_16735)	comFA	3392066..3393451 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
P0M22_RS16740 (P0M22_16740)	-	3393560..3394408 (-)	849	WP_032876160.1	DegV family protein	-
P0M22_RS16745 (P0M22_16745)	degU	3394506..3395195 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
P0M22_RS16750 (P0M22_16750)	degS	3395272..3396435 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
P0M22_RS16755 (P0M22_16755)	-	3396658..3397305 (+)	648	WP_007614107.1	YigZ family protein	-
P0M22_RS16760 (P0M22_16760)	-	3397310..3398491 (+)	1182	WP_032876157.1	LCP family protein	-
P0M22_RS16765 (P0M22_16765)	-	3398590..3399666 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
P0M22_RS16770 (P0M22_16770)	-	3399799..3400995 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=799004 P0M22_RS16750 WP_007407484.1 3395272..3396435(-) (degS) [Bacillus velezensis strain HBXN2020]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=799004 P0M22_RS16750 WP_007407484.1 3395272..3396435(-) (degS) [Bacillus velezensis strain HBXN2020]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951