Detailed information NTG0798695

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P1A17_RS09905
• Genome accession: NZ_CP119341
• Coordinates: 2006815..2007858 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain N29CSA02
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2001815..2012858

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1A17_RS09875 (P1A17_09875)	-	2002237..2003493 (-)	1257	WP_001789555.1	aminopeptidase	-
P1A17_RS09880 (P1A17_09880)	-	2003496..2003696 (-)	201	WP_000180460.1	DUF1128 family protein	-
P1A17_RS09885 (P1A17_09885)	-	2003843..2004307 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P1A17_RS09890 (P1A17_09890)	-	2004314..2004589 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P1A17_RS09895 (P1A17_09895)	-	2004867..2006084 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
P1A17_RS09900 (P1A17_09900)	vraR	2006196..2006825 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P1A17_RS09905 (P1A17_09905)	vraS	2006815..2007858 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P1A17_RS09910 (P1A17_09910)	liaF	2007855..2008556 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P1A17_RS09915 (P1A17_09915)	-	2008571..2008957 (-)	387	WP_001110179.1	hypothetical protein	-
P1A17_RS09920 (P1A17_09920)	map	2009174..2009932 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
P1A17_RS09925 (P1A17_09925)	-	2010344..2011330 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
P1A17_RS09930 (P1A17_09930)	-	2011761..2012174 (-)	414	WP_001670387.1	hypothetical protein	-
P1A17_RS09935 (P1A17_09935)	-	2012203..2012313 (-)	111	WP_031775032.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=798695 P1A17_RS09905 WP_001017131.1 2006815..2007858(-) (vraS) [Staphylococcus aureus strain N29CSA02]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=798695 P1A17_RS09905 WP_001017131.1 2006815..2007858(-) (vraS) [Staphylococcus aureus strain N29CSA02]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1